Plasma and adrenal cortisol concentrations in foetal, newborn and mother guinea-pigs during the perinatal period.
Plasma and adrenal cortisol concentrations in foetal, newborn and mother guinea-pigs during the perinatal period.
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围产期胎儿、新生儿和母豚鼠的血浆和肾上腺皮质醇浓度。
DOI：
10.1677/joe.0.0700207
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发表时间：
1976
期刊：
影响因子：
--
通讯作者：
P. Delost
中科院分区：
文献类型：
--
作者：
M. Dalle;P. Delost
在妊娠的最后6天和产后的前24小时，估计胎儿、新生儿和豚鼠母体血浆和肾上腺中皮质醇、皮质酮和可的松、肝糖原和血糖的浓度。同时测量母亲血浆中的孕酮。在胎仔血浆皮质醇水平和肝糖原的快速升高期间，未观察到胎仔肾上腺皮质醇含量的显著变化。母亲的血浆和肾上腺皮质醇浓度远高于在胎儿中观察到的浓度，并且在分娩前显著增加。在母体和胎儿中，与皮质醇相比，可的松和皮质酮在皮质类固醇中只占很小的比例。这些结果表明，胎儿肾上腺的自主能力，抑制母体分泌物在足月前，突然出现在出生时。
Concentrations of cortisol, corticosterone and cortisone in the plasma and adrenal glands, liver glycogen and plasma glucose of foetal, newborn and mother guinea-pigs were estimated during the last 6 days of pregnancy and throughout the first 24 h post partum. At the same time progesterone was measured in the plasma of the mother. During the prepartum rise in foetal plasma cortisol levels and liver glycogen, no significant change in the foetal adrenal cortisol content was observed. The plasma and adrenal cortisol concentrations of the mother were much higher than those observed in the foetus and increased significantly before parturition. In the mother as in the foetus, cortisone and corticosterone represent only a small percentage of corticosteroids compared with cortisol. These results indicate that the autonomous capacity of foetal adrenals, inhibited by maternal secretions before term, appears suddenly at birth.