GABAergic pretectal terminals contact GABAergic interneurons in the cat dorsal lateral geniculate nucleus.
GABAergic pretectal terminals contact GABAergic interneurons in the cat dorsal lateral geniculate nucleus.
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GABA 能顶盖前末梢接触猫背外侧膝状核中的 GABA 能中间神经元。
DOI：
10.1016/s0304-3940(01)02533-2
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发表时间：
2002
影响因子：
2.5
通讯作者：
Bickford,MarthaE
中科院分区：
文献类型：
--
作者：
Wang,Siting;Eisenback,Michael;Datskovskaia,Aygul;Boyce,Martin;Bickford,MarthaE
采用顺行追踪结合埋藏后免疫细胞化学染色的方法，测定了前顶盖膝状体（PT-LGN）终末及其突触后靶点的γ-氨基丁酸（GABA）含量。结果提供证据表明，PT-LGN终端是GABA能的，它们接触GABA能中间神经元。这些结果证实了以前的解剖学研究和支持的想法，PT-LGN投射功能，以解除抑制丘脑皮质细胞在背外侧膝状体核。
Anterograde tracing techniques combined with postembedding immunocytochemical staining were used to determine the gamma amino butyric acid (GABA) content of pretectogeniculate (PT-LGN) terminals and their postsynaptic targets. The results provide evidence that PT-LGN terminals are GABAergic and that they contact GABAergic interneurons. These results corroborate previous anatomical studies and support the idea that the PT-LGN projection functions to disinhibit thalamocortical cells in the dorsal lateral geniculate nucleus.