Asymmetric synthesis of fagomine and its congeners

Asymmetric synthesis of fagomine and its congeners
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DOI:
10.1016/s0957-4166(01)00136-7
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发表时间:
2001-04-17
影响因子:
--
通讯作者:
Takahata, H
Takahata, H
中科院分区:
其他
文献类型:
--
作者:
Banba, Y;Abe, C;Takahata, H

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以 D-丝氨酸衍生的 Garner 醛 5 为起始原料,通过催化闭环复分解 (RCM) 构建哌啶环,然后进行二羟基化,实现了 fagomine 及其同系物 1-3 的全合成。 (C) 2001 Elsevier Science Ltd. 保留所有权利。
The total synthesis of fagomine and its congeners 1-3 has been achieved starting from D-serine-derived Garner aldehyde 5 by catalytic ring-closing metathesis (RCM) for the construction of the piperidine ring followed by dihydroxylation. (C) 2001 Elsevier Science Ltd. All rights reserved.