"Janus"-like Cu-Fe bimetallic nanoparticles with high antibacterial activity
"Janus"-like Cu-Fe bimetallic nanoparticles with high antibacterial activity
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DOI：
10.1016/j.matlet.2019.01.105
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发表时间：
2019-05-01
影响因子：
3
通讯作者：
Lerner, M. I.
中科院分区：
文献类型：
--
作者：
Bakina, O. V.;Glazkova, E. A.;Lerner, M. I.
寻找新的有效的抗菌剂用于生物医学应用是研究人员特别关注的主题。含有生物活性金属的双金属纳米粒子是一种很有前景的抗菌剂。采用电爆炸法制备的“Janusp”型Cu/Fe纳米粒子具有与Ag纳米粒子相当的抗菌活性，且抗菌活性超过了Fe和Cu单金属纳米粒子及其混合物。Cu/Fe微粒的MIC值为3.91-250 μ g/ml。这种强的抗菌活性是由于Cu/Fe纳米粒子释放的协同杀菌Cu（2+）和Fe 3+离子。Cu/Fe纳米粒子是一种很有前途的抗菌保护技术和对抗耐药菌株的材料。(C)2019爱思唯尔B. V.保留所有权利。
The search of new efficient antibacterial agents for biomedical applications is subject of researchers special attention. Bimetallic nanoparticles containing biologically active metals are prospective antibacterial agents. The "Janusp"-like Cu/Fe nanoparticles prepared by electrical explosive of wires were found to exhibit high antibacterial activity comparable with that of Ag nanoparticles and exceed the antibacterial activity of Fe and Cu monometallic nanoparticles and their mixture. MIC values of bimetallic Cu/Fe particles are 3.91-250 mu g/ml. This strong antibacterial activity is due to the synergistic bactericidal Cu(2+)and Fe3+ ions released from Cu/Fe bimetallic nanoparticles. Cu/Fe nanoparticles are a promising material for antibacterial protection technologies and for fighting drug-resistant bacterial strains. (C) 2019 Elsevier B.V. All rights reserved.