EEG activity in girls with attention-deficit/hyperactivity disorder
EEG activity in girls with attention-deficit/hyperactivity disorder
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DOI：
10.1016/s1388-2457(02)00364-4
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发表时间：
2003-02-01
影响因子：
4.7
通讯作者：
Croft, RJ
中科院分区：
文献类型：
--
作者：
Clarke, AR;Barry, RJ;Croft, RJ
目的：本研究调查了患有注意力缺陷/多动障碍 (ADHD) 的女孩的脑电图。方法：受试者包括 100 名年龄在 8 至 12 岁之间的 ADHD 女孩和 40 名年龄和性别匹配的对照组。在闭眼休息状态下记录 21 个部位的脑电图，并进行傅里叶变换以提供总功率以及 delta、theta、alpha 和 beta 频段的相对功率估计。使用因子分析将部位分为 3 个区域，涵盖额部、中央和后部区域。将ADHD组的总功率与对照组进行比较，并对数据进行聚类分析。结果：与对照组相比，ADHD受试者具有更大的总功率、更多的相对θ以及更少的相对δ、α和β。聚类分析表明患有多动症的女孩存在两个不同的脑电图聚类。这些是（a）一个大的亚组，其特征是与对照组相比，总功率更高，相对θ更大，相对δ和β更小； (b) 一个小亚组，其高振幅 theta 活动显着增加，但所有其他波段均存在缺陷。结论：这些结果表明，患有 ADHD 的女孩的脑电图表现出异常，但其脑电图谱的差异远小于患有该疾病的男孩。结果还表明，可能有一些不同的患有多动症的女孩没有被转诊接受临床治疗。建议对该人群进行进一步研究。这项研究的意义重大，因为它是第一个单独调查患有多动症的女孩脑电图的主要研究。 (C) 2002 Elsevier Science Ireland Ltd. 保留所有权利。
Objective: This study investigated the EEG of girls with Attention-deficit/hyperactivity disorder (ADHD).Methods: Subjects consisted of 100 girls with ADHD between the ages of 8 and 12 years and 40 age- and gender-matched controls. EEG was recorded from 21 sites during an eyes-closed resting condition and Fourier transformed to provide estimates for total power, and relative power in the delta, theta, alpha and beta bands. Factor analysis was used to group sites into 3 regions, covering frontal, central and posterior regions. The total ADHD group was compared to the control group as well as the data being subjected to cluster, analysis.Results: The ADHD subjects had greater total power, more relative theta, and less relative delta, alpha and beta than controls. Cluster analysis indicated the presence of two distinct EEG clusters of girls with ADHD. These were (a) a large subgroup characterized by increased total power, more relative theta, and less relative delta and beta than control subjects; and (b) a small subgroup with a substantially-increased amount of high amplitude theta activity, with deficiencies in all other bands.Conclusions: These results indicate that girls with ADHD exhibit abnormalities in their EEGs, but there is far less variance in their EEG profiles than is found in boys with the disorder. The results also suggest that there may be distinct groups of girls with ADHD who are not being referred for clinical treatment. Recommendations are made for further research in this population. This study is significant in that it is the first major study to separately investigate the EEG of girls with ADHD. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.