Macular electroretinogram as a function of age of subjects
Macular electroretinogram as a function of age of subjects
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黄斑视网膜电图作为受试者年龄的函数
DOI：
10.1007/bf00154734
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发表时间：
1988
影响因子：
1.4
通讯作者：
G. Moretti
中科院分区：
文献类型：
--
作者：
B. Bagolini;V. Porciatti;B. Falsini;G. Scalia;M. Neroni;G. Moretti
在34名年龄从16岁到74岁的正常受试者中记录了黄斑和黄斑旁视网膜电图对两个相邻检查（6度/侧）的反应，以恒定的平均亮度交替。黄斑视网膜电图的振幅随年龄增长而逐渐下降（R =-0.42; P = 0.013）。黄斑和黄斑旁反应的振幅比与年龄无关（R = -0.21; P = 0.22）。我们研究中黄斑视网膜电图中的视网膜电图相关变化与以前的解剖学和功能研究一致，表明20岁以上的光感受器退化。这些结果表明，这项技术可能用于黄斑变性的未来研究。
Macular and paramacular electroretinograms in response to two adjacent checks (6 deg/side), alternating at constant mean luminance, were recorded in 34 normal subjects ranging in age from 16 to 74 years. The macular electroretinogram declines progressively in amplitude with age (R = −0.42; P = 0.013). The amplitude ratio between macular and paramacular responses tends to be independent of age (R = -0.21; P = 0.22).Age-related changes in the macular electroretinogram shown in our study are consistent with previous anatomical and functional studies, which indicate a deterioration of photoreceptors beyond 20 years of age. These results suggest a possible use of this technique for future studies on macular degeneration.