Erectile dysfunction
Erectile dysfunction
复制标题
DOI：
10.1016/s0022-5347(05)00309-5
复制
发表时间：
2006-03-01
影响因子：
6.6
通讯作者：
Burnett, AL
中科院分区：
文献类型：
--
作者：
Burnett, AL
目的：概述了男性ED的流行病学、病理生理学和治疗方面的最新概念。材料和方法：对ED管理领域的已发表文献和由共识机构推动的当前范例进行了综述。结果：勃起功能障碍是一种受阴茎激素、局部生化和生物力学/结构因素调节的神经血管现象。ED曾经被认为是主要的心理问题，现在被认为是主要的器质性病因。它与心血管疾病有显著关联，可作为后续心血管事件的先兆。目标导向的评估和管理意味着关注患者（和伴侣）对各种治疗方案的偏好。这些选择范围从口服药理学药物到手术，并且可以继续进行。按照循序渐进的管理方法。心理社会干预也可以作为有用的治疗辅助手段。结论：ED在大多数患者中是一种高度可控的疾病。患者和他的伴侣在决策过程中发挥着不可或缺的作用，因为关于性活动重要性的偏好，以及治疗的风险和益处在个人之间会有很大差异。
Purpose: An overview of the latest concepts advanced with regard to the epidemiology, pathophysiology, and management of male ED is provided.Materials and Methods: Published literature and current paradigms promoted by consensus bodies in the field with regard to the management of ED were reviewed.Results: ED is a neurovascular phenomenon modulated by hormonal, local biochemical, and biomechanical/structural factors of the penis. Once viewed primarily as a psychological issue, ED is now understood to represent predominantly organic etiologies. It has a significant association with cardiovascular disease and could serve as a harbinger of subsequent cardiovascular events. Goal directed assessment and management implies a focus on patient (and partner) preferences regarding various treatment options. These options range from oral pharmacological agents to surgery and may be pursued. according to a stepwise management approach. Psychosocial interventions also may serve as useful therapeutic adjuncts.Conclusions: ED is a highly manageable disorder in most patients. The patient and his partner have integral roles in the decision making process, since preferences regarding the importance of sexual activity, and the risks and benefits of treatment will vary greatly among individuals.