A New Alkenylmethylresorcinol from the Fruits of Ardisia kivuensis
A New Alkenylmethylresorcinol from the Fruits of Ardisia kivuensis
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DOI：
10.1177/1934578x1601100527
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发表时间：
2016-05
影响因子：
1.8
通讯作者：
Y. M. M. Nguekeu-Y.-M.-M.-Nguekeu-8237747;B. L. Ndontsa;R. Mbouangouere;M. Awouafack;Takuya Ito;P. Tane;H. Morita
中科院分区：
文献类型：
--
作者：
Y. M. M. Nguekeu-Y.-M.-M.-Nguekeu-8237747;B. L. Ndontsa;R. Mbouangouere;M. Awouafack;Takuya Ito;P. Tane;H. Morita
采用反复硅胶柱层析和Sephadex LH-20柱层析，对紫草果实乙醇提取物进行了植物化学研究，得到了一个新的烯基甲基间苯二酚--青蒿素III(1)和3个已知化合物齐墩果酸、β-谷甾醇和二十五烷酸。1的结构经波谱分析(核磁共振和质谱学)确证，并与文献报道的数据进行了比较。化合物1具有较弱的抗氧化活性(IC_(50)109.8μg/mL)，而其他化合物与L-抗坏血酸(IC_(50)3.9μg/mL)相比没有抗氧化活性。
The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).