Periodontal conditions in juvenile idiopatic arthritis.
Periodontal conditions in juvenile idiopatic arthritis.
复制标题
幼年特发性关节炎的牙周状况。
DOI：
10.23736/s0026-4970.17.03937-1
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发表时间：
2017
影响因子：
--
通讯作者：
G. Farronato
中科院分区：
文献类型：
--
作者：
C. Maspero;L. Giannini;G. Galbiati;C. Prevedello;G. Farronato
背景
牙周炎和幼年特发性关节炎（JIA）之间可能的关系现在大多是未知的，但这两种疾病有共同的特点。本研究的目的是评估依那西普（Enbrel®）对JIA患儿牙周状况的影响。
方法
本研究选择了三组患者。第一种是接受依那西普（Enbrel®）药物治疗的JIA受试者。第二组由接受其他药物治疗的受试者组成，第三组由健康受试者组成。每组选择20名受试者。对每个受试者进行两项牙周评分：菌斑指数和探诊出血。为了检查该方法的可靠性，一个月后在所有3组中进行了第二次配准。进行统计Kruskal-Wallis检验。
结果
第一组的平均菌斑指数为48%，第二组为37%，对照组为20%。第一组的平均出血指数为5%，第二组为5%，对照组为9%。
结论
依那西普似乎可以减轻JIA患儿的牙周炎症。
BACKGROUND
The possible relationship between periodontitis and juvenile idiopathic arthritis (JIA) is now mostly unknown but there are common characteristics in these two diseases. The purpose of this study is to evaluate etanercept (Enbrel®) effects on periodontal conditions of children affected by JIA.
METHODS
For this study three group of patients were selected. The first one is represented by JIA subjects in pharmacologic therapy with etanercept (Enbrel®). The second one was composed by subjects in pharmacologic therapy with other drugs and the third one by healthy subjects. Twenty subjects for each group were selected. For each subject two periodontal scores were taken: Plaque Index and bleeding on probing. In order to check the reliability of the method a second registration has been performed in all the 3 groups after one month. A statistic Kruskal-Wallis test was performed.
RESULTS
The average Plaque Index was 48% in the first group, 37% in the second group and 20% in the control group. The average Bleeding Index was 5% in the first group, 5% in the second group and 9% in the control group.
CONCLUSIONS
Etanercept seems to reduce periodontal inflammation in children affected by JIA as the other therapy.