Stereotactic Technique for Radio-frequency Antenna Implantation for Brain Tumor Treatment
Stereotactic Technique for Radio-frequency Antenna Implantation for Brain Tumor Treatment
复制标题
射频天线植入立体定向技术治疗脑肿瘤
DOI：
10.3191/thermalmedicine.21.221
复制
发表时间：
2005
期刊：
影响因子：
--
通讯作者：
I. Grinev
中科院分区：
文献类型：
--
作者：
Hideaki Takahashi;R. Tanaka;T. Uzuka;I. Grinev
目的：在过去的 20 年里，我们开发了射频 (RF) 间质热疗的技术和临床经验。该技术特别适用于无法切除的肿瘤的治疗以及患有恶性脑肿瘤的老年患者的治疗。在本报告中，我们介绍了用于间质热疗的立体定向瘤内植入电极（射频天线），并介绍了其成就和并发症发生率。我们的目的是评估立体定向植入技术用于脑热疗的可行性。方法：共对125例脑肿瘤热疗患者进行144例手术（胶质瘤108例，转移瘤24例，恶性淋巴瘤5例，脑膜瘤5例，其他肿瘤2例）。在局部麻醉下使用立体定向装置将射频天线和热敏电阻探针导管插入肿瘤中。我们通过术后颅骨照片和脑部计算机断层扫描（CT）确认了肿瘤中的电极位置以及出血等并发症。结果：射频天线插入次数分别为 85 例、2 例、43 例、3 例、4 例、12 例、5 例、6 例。 144 例手术中有 138 例成功实现了射频天线的手术插入（95.8%）。其中6例患者中，3例术后出现瘤内出血，1例患者出现白酒，另外2例患者出现天线误植。未完成率为4.2%。结论：射频天线立体定向植入是一种安全有效的脑肿瘤间质热治疗技术。
Purpose : Over the past 20 years we have developed techniques and clinical experience of radio frequency (RF) interstitial hyperthermia. This technique is particularly applicable in the treatment of unresectable tumors and in the management of elderly patients with malignant brain tumors. In this report, we introduce stereotactic intratumoral implantation of electrodes (RF antennas) for interstitial hyperthermia and we also present the achievement and complication rate. Our objective was to assess the feasibility of the stereotactic implantation technique for brain hyperthermia. Methods : A total of 144 procedures (108 for gliomas, 24 for metastatic tumors, 5 for malignant lymphomas, 5 for meningiomas, and 2 for other tumors) have been performed to treat 125 patients with hyperthermia for brain tumor. RF antennas and catheters for thermistor probes were inserted into the tumor using a stereotactic apparatus under local anesthesia. We confirmed the electrode position in the tumor and complications such as hemorrhage in postoperative craniogram and brain computed tomography (CT). Results : The numbers of RF antenna insertions were one in each of 85 cases, two in 43 cases, three in 2 cases, four in 12 cases, five in 1 case, and six in 1 case. Surgical insertion of RF antennas was achieved successfully in 138 of 144 procedures (95.8%). In six of these patients, intratumoral hemorrhage was observed after surgery in 3 patients, one patient had liquorrhea, and antennas were misimplanted in another 2 patients. Incompletion rate was 4.2%. Conclusion : Stereotactic implantation of RF antennas was a safe and effective technique for interstitial hyperthermic treatment of brain tumors.
间质照射和热疗用于治疗复发性恶性脑肿瘤。
影响因子：
4.8
作者：
Sneed,PK;Stauffer,PR;Gutin,PH;Phillips,TL;Suen,S;Weaver,KA;Lamb,SA;Ham,B;Prados,MD;Larson,DA
通讯作者：
Larson,DA
模板引导立体定位脑植入物的治疗计划。
DOI：
10.1016/0360-3016(90)90422-g
发表时间：
1990
期刊：
International journal of radiation oncology, biology, physics
影响因子：
--
作者：
Lulu,BA;Lutz,W;Stea,B;Cetas,TC
通讯作者：
Cetas,TC
脑肿瘤间质热放射治疗：I 期临床试验的初步结果。
DOI：
10.1016/0360-3016(90)90359-r
发表时间：
1990
期刊：
International journal of radiation oncology, biology, physics
影响因子：
--
作者：
Stea,B;Cetas,TC;Cassady,JR;Guthkelch,AN;Iacono,R;Lulu,B;Lutz,W;Obbens,E;Rossman,K;Seeger,J
通讯作者：
Seeger,J