STRAIN VARIATION OF LYME-DISEASE SPIROCHETES ISOLATED FROM IXODES-RICINUS TICKS AND RODENTS COLLECTED IN 2 ENDEMIC AREAS IN SWITZERLAND
STRAIN VARIATION OF LYME-DISEASE SPIROCHETES ISOLATED FROM IXODES-RICINUS TICKS AND RODENTS COLLECTED IN 2 ENDEMIC AREAS IN SWITZERLAND
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DOI：
10.1093/jmedent/32.4.433
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发表时间：
1995-07-01
影响因子：
2.1
通讯作者：
GERN, L
中科院分区：
文献类型：
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作者：
HUMAIR, PF;PETER, O;GERN, L
莱姆病、疏螺旋体基因种、啮齿动物宿主和蓖麻硬蜱之间的关系。在瑞士的两个流行区研究了蜱。耳穿孔活组织检查和内脏取样用于从小型哺乳动物，森林姬鼠L.，A. flavicollis Melchior，灰腹鼠Clethrionomys glareolus Schreber.从啮齿动物的耳组织和脾脏中分离出螺旋体。分离株是同质的，属于鉴定为B的II型组。afzelii（Canica，Nato，du Merle，Mazie，Baranton and Postic）.我们的数据表明，B。afzelii和啮齿动物水库在欧洲的焦点。还从野外采集的I.来自同一研究区域的蓖麻蜱。蛋白质和抗原分析表明，一个以上的基因种存在于蜱人口。这表明其他脊椎动物宿主可能作为与莱姆病有关的其他疏螺旋体基因种的储存库。
The relationship among Lyme borreliosis, Borrelia genospecies, rodent reservoirs, and Ixodes ricinus L. ticks was studied in two endemic areas in Switzerland. Ear punch biopsies and sampling of internal organs were used to isolate Borrelia burgdorferi (Johnson, Schmid, Hyde, Steigerwalt and Brenner) from small mammals, Apodemus sylvaticus L., A. flavicollis Melchior, Clethrionomys glareolus Schreber. Spirochetes were isolated from ear tissue and spleen of the rodents. Isolates were homogeneous and belonged to typing group II identified as B. afzelii (Canica, Nato, du Merle, Mazie, Baranton and Postic). Our data show that a specific association exists between B. afzelii and rodent reservoirs in European foci. Borreliae were also isolated from field-collected I. ricinus ticks from the same study areas. Proteinic and antigenic analysis indicated that more than one genospecies were present in the tick population. This suggests that other vertebrate hosts may serve as reservoirs of other Borrelia genospecies implicated with Lyme disease.