Development of health-related waist circumference thresholds within BMI categories
Development of health-related waist circumference thresholds within BMI categories
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DOI：
10.1038/oby.2004.137
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发表时间：
2004-07-01
期刊：
影响因子：
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通讯作者：
Katzmarzyk, PT
中科院分区：
文献类型：
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作者：
Ardern, CI;Janssen, I;Katzmarzyk, PT
目的：开发和交叉验证BMI类别中的腰围（WC）阈值。将导出值的效用与单个WC阈值进行比较（女性，88 cm;男性，102 cm）。研究方法和程序：样本包括正常体重的成年人（BMI = 18.5至24.9），超重（BMI = 25至29.9），肥胖I（BMI = 30至34.9）和肥胖II+（BMI大于或等于35）来自第三次美国国家健康和营养检查调查（NHANES 111; n = 11，968）和加拿大心脏健康调查（CHHS; n = 6286）。受试者工作特征曲线用于确定最佳WC阈值，该阈值可预测使用NHANES III的BMI类别中的冠状动脉事件高风险（Frachial评分的前五分位数）。使用CHHS交叉验证BMI特定WC阈值。结果：不同BMI类别的最佳WC阈值增加，男性从87厘米增加到124厘米，女性从79厘米增加到115厘米。验证研究表明，改善的灵敏度和特异性与BMI特定的WC阈值相比，单一thresholds.Discussion：与推荐的WC奥尔兹相比，BMI特定的值提高了健康风险的识别。在正常体重、超重、肥胖1和肥胖II+患者中，男性WC临界值分别为90、100、110和125 cm，女性分别为80、90、105和115 cm，可用于识别风险增加的患者。
Objective: To develop and cross-validate waist circumference (WC) thresholds within BMI categories. The utility of the derived values was compared with the single WC thresholds (women, 88 cm; men, 102 cm) recommended by NIH and Health Canada.Research Methods and Procedures: The sample included adults classified as normal weight (BMI = 18.5 to 24.9), overweight (BMI = 25 to 29.9), obese I (BMI = 30 to 34.9), and obese II+ (BMI greater than or equal to 35) from the Third U.S. National Health and Nutrition Examination Survey (NHANES 111; n = 11,968) and the Canadian Heart Health Surveys (CHHS; n = 6286). Receiver operating characteristic curves were used to determine the optimal WC thresholds that predicted high risk of coronary events (top quintile of Framingham scores) within BMI categories using the NHANES III. The BMI-specific WC thresholds were cross-validated using the CHHS.Results: The optimal WC thresholds increased across BMI categories from 87 to 124 cm in men and from 79 to 115 cm in women. The validation study indicated improved sensitivity and specificity with the BMI-specific WC thresholds compared with the single thresholds.Discussion: Compared with the recommended WC thresh olds, the BMI-specific values improved the identification of health risk. In normal weight, overweight, obese 1, and obese II+ patients, WC cut-offs of 90, 100, 110, and 125 cm in men and 80, 90, 105, and 115 cm in women, respectively, can be used to identify those at increased risk.