FruR mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli
FruR mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli
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DOI：
10.1128/jb.178.1.280-283.1996
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发表时间：
1996-01-01
影响因子：
3.2
通讯作者：
Saier, MH
中科院分区：
文献类型：
--
作者：
Bledig, SA;Ramseier, TM;Saier, MH
研究了pykF-lacZ融合体的表达作为野生型菌株和缺乏或过量产生大肠杆菌FruR蛋白的菌株中碳源的函数。FruR通过在产芽孢条件下比在糖酵解条件下更强烈地抑制pykF表达来控制对碳源的响应，这是一种黑麦术语分解代谢物活化的现象。
Expression of a pykF-lacZ fusion was studied as a function of the carbon source in wild-type strains and strains lacking or overproducing the FruR protein of Escherichia coli, FruR controls the response to the carbon source by repressing pykF expression more strongly under gluconeogenic than under glycolytic conditions, a phenomenon rye term catabolite activation.