Magnetic properties of human hippocampal tissue - Evaluation of artefact and contamination sources
Magnetic properties of human hippocampal tissue - Evaluation of artefact and contamination sources
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DOI：
10.1016/0361-9230(95)02132-9
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发表时间：
1996-01-01
影响因子：
3.8
通讯作者：
Grassi, P
中科院分区：
文献类型：
--
作者：
Dobson, J;Grassi, P
调查的可能性，死后化学改变或污染是负责最近的结果表明磁铁矿的存在，在人脑组织中，并确定磁铁矿是否存在于活的脑组织中，我们检查了组织样本切除6例患者在杏仁核campectomy手术。在手术室中，将组织样本密封在无菌小瓶中，并在取出后直接放入液氮中，以防止脑细胞死亡后组织化学发生变化。测量组织的低温磁性以确定组织中铁磁或亚铁磁材料的存在。这些实验的结果表明，磁铁矿存在于组织中。此外，旨在控制空气污染和手术过程中烧灼血管期间的污染的实验结果表明，这些不是组织中磁铁矿污染的重要来源。
To investigate the possibility that postmortem chemical alteration or contamination is responsible for recent results indicating the presence of magnetite in human brain tissue and to determine whether magnetite is present in living brain tissue, we examined tissue samples resected from six patients during amygdalohippocampectomy operations. The tissue samples were sealed in sterilized vials in the operating theater and placed into liquid nitrogen directly after removal to prevent changes in tissue chemistry after the death of the brain cells. The low temperature magnetic properties of the tissue were measured to determine the presence of ferro- or ferrimagnetic material in the tissue. The results of these experiments indicate that magnetite is present in the tissue. In addition, results of experiments designed to control for airborne contamination and contamination during cauterization of vessels during surgery indicate that these are not significant sources of magnetite contamination in the tissue.