Nickel-Catalyzed Cross-Coupling of Aryl Phosphates with Arylboronic Acids
Nickel-Catalyzed Cross-Coupling of Aryl Phosphates with Arylboronic Acids
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镍催化芳基磷酸酯与芳基硼酸的交叉偶联
DOI：
10.1021/jo2000034
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发表时间：
2011-04-01
影响因子：
3.6
通讯作者：
Cheng, Chien-Hong
中科院分区：
文献类型：
--
作者：
Chen, Hu;Huang, Zhongbin;Cheng, Chien-Hong
本文报道了以Ni(PCy(3))(2)Cl(2)为催化剂的芳基磷酸酯的Suzuki-Miyaura交叉偶联反应。通过合成40多个联芳基和构建复杂的有机分子，证明了底物范围宽和效率高。利用芳基磷酸盐相对于芳基卤化物较差的反应性，在Pd和Ni催化剂上进行选择性交叉偶联，成功地合成了聚芳烃。
The Suzuki-Miyaura cross-coupling of aryl phosphates using Ni(PCy(3))(2)Cl(2) as an inexpensive, bench-stable catalyst is described. Broad substrate scope and high efficiency are demonstrated by the syntheses of more than 40 biaryls and by constructing complex organic molecules. The poor reactivity of aryl phosphates relative to aryl halides is successfully employed to construct polyarenes by selective cross-coupling using Pd and Ni catalysts.