Inhibitory effects of oolong tea extract on caries-inducing properties of mutans streptococci
Inhibitory effects of oolong tea extract on caries-inducing properties of mutans streptococci
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DOI：
10.1159/000016549
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发表时间：
1999-11-01
期刊：
影响因子：
4.2
通讯作者：
Ooshima, T
中科院分区：
文献类型：
--
作者：
Matsumoto, M;Minami, T;Ooshima, T
研究了乌龙茶提取物（OTE）对变形链球菌致龋作用的体外抑制作用。OTE降低了变形链球菌的产酸速率，并伴随着变形链球菌生长速率的延迟，而层析分离的乌龙茶多酚（OTF 6）的作用很弱。另一方面，两种乌龙茶产品都降低了本研究中检测的几乎所有口腔链球菌的细胞表面疏水性，并且还诱导了变形链球菌、口腔链球菌、血链球菌或戈登链球菌的细胞聚集。在这些反应中，OTF 6显示出比OTE更显著的活性。乌龙茶产品抑制变形链球菌对唾液包被的羟基磷灰石的粘附。这些结果表明OTF 6可以通过降低变形链球菌的疏水性来抑制细菌对牙齿表面的粘附，OTE可能通过降低产酸速率而抑制变形链球菌的致龋活性。
The inhibitory effects of oolong tea extract (OTE) on the caries-inducing properties of mutans streptococci were examined in vitro. OTE reduced the rate of acid production by mutans streptococci accompanied with the retardation of growth rate of mutans streptococci, while the action by chromatographically isolated oolong tea polyphenol (OTF6) was weak. On the other hand, both oolong tea products decreased cell surface hydrophobicity of almost all the oral streptococci examined in the present study, and also induced cellular aggregation of Streptococcus mutans, Streptococcus oralis, Streptococcus sanguis or Streptococcus gordonii, In these reactions, OTF6 showed a more pronounced activity than OTE, Furthermore, the oolong tea products inhibited the adherence of mutans streptococci to saliva-coated hydroxyapatite, These results suggest that OTF6 may inhibit bacterial adherence to the tooth surfaces by reducing the hydrophobicity of mutans streptococci, and OTE may inhibit caries-inducing activity of mutans streptococci by reducing the rate of acid production.