Renal trehalase: function and development.

Renal trehalase: function and development.
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DOI:
10.1016/0300-9629(90)90015-k
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发表时间:
1990
期刊:
Comparative biochemistry and physiology. A, Comparative physiology
影响因子:
--
通讯作者:
J. Riby;S. Sunshine;N. Kretchmer
J. Riby;S. Sunshine;N. Kretchmer
中科院分区:
其他
文献类型:
--
作者:
J. Riby;S. Sunshine;N. Kretchmer

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1.将海藻糖注射到血流中后,在家兔尿液中未发现海藻糖,直至血液中海藻糖浓度超过0.6 mg/ml。2.当血液中的糖浓度升高时,家兔尿液中不存在海藻糖,这支持肾海藻糖酶在肾脏中起消化酶作用的假设。3.大鼠肾脏不具有海藻糖酶,海藻糖的排泄与血液中海藻糖的浓度直接相关。4.尽管它们具有许多共同的结构和酶特性,但在肾脏和肠道中的dispronidases表达存在差异。
1. Following injection of trehalose into the bloodstream, no trehalose was found in urine of rabbits until the concentration of trehalose in blood exceeded 0.6 mg/ml. 2. Absence of trehalose in urine of the rabbit when the concentration of the sugar in blood is elevated supports the hypothesis that renal trehalase functions as a digestive enzyme in kidney. 3. The rat does not possess renal trehalase, and excretion of trehalose was in direct relation to the concentration of trehalose in blood. 4. There are differences in expression of the disaccharidases in kidney and intestine although they share many structural and enzymatic characteristics.