Anthralin Therapy for Alopecia Areata
Anthralin Therapy for Alopecia Areata
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蒽林疗法治疗斑秃
DOI：
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发表时间：
1985
影响因子：
3.6
通讯作者：
R. Spielvogel
中科院分区：
文献类型：
--
作者：
D. Nelson;R. Spielvogel
摘要：据报道，局部应用激惹性接触性皮炎对斑秃有治疗作用。进行了一项初步的临床研究，以确定局部应用足够低的剂量仅产生轻微接触性皮炎是否会产生类似的治疗反应。研究中的患者都没有从这种低剂量方案中获得任何好处。如果对斑秃的治疗是有益的，那么明显的刺激性接触性皮炎是必要的。
ABSTRACT: Topical anthralin application producing a brisk irritant contact dermatitis has been reported to have therapeutic benefit in alopecia areata. A pilot clinical study was undertaken to determine whether topical anthralin application in doses low enough to produce only minimal contact dermatitis would produce a similar therapeutic response. None of the patients in the study received any benefit from this low‐dose regimen. If anthralin is of benefit in the therapy of alopecia areata, a significant irritant contact dermatitis is apparently required.