A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states
A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states
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DOI：
10.1177/0272989x0102100102
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发表时间：
2001-01-01
影响因子：
3.6
通讯作者：
Kind, P
中科院分区：
文献类型：
--
作者：
Badia, X;Roset, M;Kind, P
很少有研究比较不同国家获得的健康状况偏好值。本研究比较了西班牙和英国（UK）EuroQol-5D健康状态的时间权衡值。在这两个国家中遵循相同的偏好诱导协议。直接评定的43个健康状态的值的差异进行了分析，使用t检验，并通过汇总2个值集和使用虚拟变量来分析国家效应的维度和严重程度的随机效应模型生成的回归系数进行了比较。对于较轻的健康状态，西班牙和英国的值分配是相似的;对于中等健康状态，西班牙的值都高于和低于英国的值，而对于比死亡更差的健康状态，英国的值一般高于西班牙的值。有34.9%的健康状况直接评价的值有统计学显著差异（P < 0.01），国家之间的一些偏好逆转。英国评分者认为疼痛/不适和焦虑/抑郁的维度更重要，而西班牙评分者更重视移动性和自我护理的功能维度。需要进一步分析，以确定这些差异如何影响成本效益和成本效用分析。
Few studies have compared preference values for health states obtained in different countries. The present study compared Spanish and United Kingdom (UK) time trade-off values for EuroQol-5D health states. The same preference elicitation protocol was followed in both countries. Differences in values for 43 health states rated directly were analyzed using t tests, and regression coefficients generated by random effects modeling were compared by aggregating the 2 value sets and using dummy variables to analyze country effect by dimension and level of severity. For the milder health states, Spanish and UK value assignation was similar; for intermediate health states, Spanish values were both higher and lower than UK values, whereas for health states worse than death, UK values were generally higher than Spanish values. There were statistically significant differences (P < 0.01) in values for 34.9% of health states rated directly, and some preference reversals between countries. UK raters ascribed greater importance to dimensions of pain/discomfort and anxiety/depression, whereas Spanish raters placed more importance on functional dimensions of mobility and self-care. Further analysis is required: to determine how these differences affect cost-effectiveness and cost-utility analyses.