Genome Mining Reveals Two Novel Bacterial Sesquiterpene Cyclases: (-)-Germacradien-4-ol and (-)-epi-α-Bisabolol Synthases from Streptomyces citricolor
Genome Mining Reveals Two Novel Bacterial Sesquiterpene Cyclases: (-)-Germacradien-4-ol and (-)-epi-α-Bisabolol Synthases from Streptomyces citricolor
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DOI：
10.1002/cbic.201100418
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发表时间：
2011-10-17
期刊：
影响因子：
3.2
通讯作者：
Ohnishi, Yasuo
中科院分区：
文献类型：
--
作者：
Nakano, Chiaki;Kudo, Fumitaka;Ohnishi, Yasuo
现在在细菌中发现：越来越多的基因组序列表明细菌拥有各种萜类环化酶基因。本文描述了在橙色链霉菌基因组草稿序列中发现的两个倍半萜环化酶(SC)基因的特征。我们的研究有力地支持了这样的观点，即基因组挖掘是揭示细菌中萜类多样性的有用方法。
Now found in bacteria: An increasing number of genome sequences indicate that bacteria possess a variety of terpenoid cyclase genes. The characterization of two sesquiterpene cyclase (SC) genes found in the draft genome sequence of Streptomyces citricolor is described here. Our study strongly supports the idea that genome mining is a useful approach in revealing the terpenoid diversity in bacteria.