Effect of treatment with Liu‐Jun‐Zi‐Tang (TJ‐43) on gastric emptying and gastrointestinal symptoms in dyspeptic patients

Effect of treatment with Liu‐Jun‐Zi‐Tang (TJ‐43) on gastric emptying and gastrointestinal symptoms in dyspeptic patients
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六君子汤(TJ-43)治疗对消化不良患者胃排空和胃肠道症状的影响

DOI:
10.1111/j.1365-2036.1993.tb00120.x
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发表时间:
1993
影响因子:
7.6
通讯作者:
H. Iishi
H. Iishi
中科院分区:
医学1区
文献类型:
--
作者:
M. Tatsuta;H. Iishi

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观察中药六君子汤(TJ-43)对42例慢性特发性消化不良患者胃排空和胃肠症状的影响。随机分组,22例患者口服2.5g TJ-43,每日3次,20例患者接受安慰剂治疗。对乙酰氨基酚吸收法测定胃排空。治疗7天后,服用TJ-43的患者胃排空明显加快,胃肠道症状明显减轻。安慰剂治疗没有产生明显的效果。提示TJ-43对胃排空有促进作用,对慢性消化不良有一定的治疗作用。
The effects of treatment with the Chinese herbal medicine Liu‐Jun‐Zi‐Tang (TJ‐43) on gastric emptying and gastrointestinal symptoms were investigated in 42 patients with chronic idiopathic dyspepsia. By random allocation, 22 patients received oral treatment with 2.5 g TJ‐43 three times daily, and 20 patients received placebo. Gastric emptying was measured by the acetaminophen absorption method. After 7 days of treatment, gastric emptying was significantly accelerated and gastrointestinal symptoms were significantly reduced in patients treated with TJ‐43. Placebo treatment produced no significant effects. These findings indicate that TJ‐43 had a prokinetic action on gastric emptying and that it was useful in treating chronic dyspepsia.
高效液相色谱法测定血浆中对乙酰氨基酚:单剂量药代动力学研究。
DOI: 10.1016/s0378-4347(00)84226-7
发表时间: 1981
期刊: Journal of chromatography
影响因子: --
作者:
Ameer,B;Greenblatt,DJ;Divoll,M;Abernethy,DR;Shargel,L
通讯作者: Shargel,L