New developments of the IMPAX small-volume automated crystallization system.
New developments of the IMPAX small-volume automated crystallization system.
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DOI：
10.1107/s0907444993013320
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发表时间：
1994-07
期刊：
影响因子：
--
通讯作者：
N. Chayen;P. D. Shaw Stewart;P. Baldock
中科院分区：
文献类型：
--
作者：
N. Chayen;P. D. Shaw Stewart;P. Baldock
介绍了Impax自动结晶系统的最新进展。在该系统中引入了五通道微尖，从而为进行实验提供了额外的自由度。介绍了一种新的鼠标驱动的筛选程序，它为设计和执行涵盖新结晶条件的屏幕创造了更广泛的范围。硬件已经被改装，因此该系统也可以用于建立蒸汽扩散试验。一种简单的蒸气扩散容器的设计，适用于2-15微升的静置滴定，使用较小的储罐体积(高达100微升)，便于大规模的系统试验。
Recent developments of the IMPAX system for automated crystallization are presented. A five-channel microtip has been introduced into the system thereby providing an extra degree of freedom for carrying out experiments. A new mouse-driven program for screening has been introduced, which creates a much wider scope for designing and executing screens covering new conditions of crystallization. The hardware has been adapted so that the system can also be used to set up vapour-diffusion trials. A simple design of a vapour-diffusion vessel, suitable for sitting drops of 2-15 microl, using smaller reservoir volumes (up to 100 microl), facilitates large-scale systematic trials.