Aberrant distribution of tyrosine hydroxylase and substance P in infants with brain‐stem infarction
Aberrant distribution of tyrosine hydroxylase and substance P in infants with brain‐stem infarction
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脑干梗死婴儿酪氨酸羟化酶和 P 物质分布异常
DOI：
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发表时间：
1994
期刊：
影响因子：
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通讯作者：
L. Becker
中科院分区：
文献类型：
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作者：
A. Nishimura;S. Takashima;T. Mito;L. Becker
应用免疫组织化学方法，对4例远期脑干或小脑梗塞合并呼吸异常的婴幼儿脑干内酪氨酸羟化酶(TH)和P物质(SP)的分布进行了研究。TH免疫反应细胞和SP免疫反应纤维位于梗死区被盖内及周围，其数量和部位与正常对照组不同。SP和TH的异常定位可能代表了与梗塞的解决相关的修复过程的改变，并可能与呼吸控制异常或猝死有关。
The distribution of tyrosine hydroxylase (TH) and substance P (SP) was examined in the brain‐stem of 4 infants with respiratory abnormalities associated with remote brain‐stem or cerebellar infarction utilizing immunohistochemical methods. TH‐immunoreactive cells and SP‐immunoreactive fibers were found in and around the area of the infarction in the tegmentum, in amounts and sites different from that seen in controls. The aberrant localization of SP and TH may represent an altered repair process associated with resolution of the infarction and may be related to abnormal respiratory control or sudden death.
DOI：
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发表时间：
1982
期刊：
The Journal of comparative neurology
影响因子：
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作者：
J. Priestley;P. Somogyi;A. Cuello
通讯作者：
J. Priestley;P. Somogyi;A. Cuello