Long-term stability of spontaneous otoacoustic emissions
Long-term stability of spontaneous otoacoustic emissions
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DOI：
10.1121/1.3097768
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发表时间：
2009-05-01
影响因子：
2.4
通讯作者：
Burns, Edward M.
中科院分区：
文献类型：
--
作者：
Burns, Edward M.
自发性耳声发射（SOAE）进行了纵向测量，持续时间长达19.5年。受试者的初始年龄范围为6至41岁。最令人信服的发现是所有受试者的所有排放频率降低，以%/年计近似呈线性，平均为0.25%/年。SOAE水平也倾向于随着年龄的增长而下降，这一趋势是显著的，但在受试者内部或跨受试者的排放中并不一致。个体SOAE水平可能随年龄增加而降低、增加或保持相对恒定。注意到几种类型的频率/水平不稳定性，其中耳内的一些SOAE相互作用，使得它们的水平呈负相关。这些不稳定往往持续多年。还在2只雌性动物的妊娠过程中测量了SOAE。未观察到SOAE水平或频率的变化，其大于月经周期中女性报告的变化，表明女性性腺激素水平对SOAE频率或水平没有显著的直接影响。(C)2009年，美国声学学会。[DOI 10.1121/1.3097768]
Spontaneous otoacoustic emissions (SOAEs) were measured longitudinally for durations up to 19.5 years. Initial ages of the subjects ranged from 6 to 41 years. The most compelling finding was a decrease in frequency of all emissions in all subjects, which was approximately linear in %/year and averaged 0.25%/year. SOAE levels also tended to decrease with age, a trend that was significant, but not consistent across emissions, either within or across subjects. Levels of individual SOAEs might decrease, increase, or remain relatively constant with age. Several types of frequency/level instabilities were noted in which some SOAEs within an ear interacted such that their levels were negatively correlated. These instabilities often persisted for many years. SOAEs were also measured in two females over the course of their pregnancies. No changes in SOAE levels or frequencies were seen, that were larger than have been reported in females over a menstrual cycle, suggesting that levels of female gonadal hormones do not have a significant direct effect on SOAE frequencies or levels. (C) 2009 Acoustical Society of America. [DOI: 10.1121/1.3097768]