A computer program for aligning a cDNA sequence with a genomic DNA sequence

A computer program for aligning a cDNA sequence with a genomic DNA sequence
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DOI:
10.1101/gr.8.9.967
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发表时间:
1998-09-01
期刊:
影响因子:
7
通讯作者:
Miller, W
Miller, W
中科院分区:
生物学1区
文献类型:
--
作者:
Florea, L;Hartzell, G;Miller, W

文献摘要

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We address the problem of efficiently aligning a transcribed and spliced DNA sequence with a genomic sequence containing that gene, allowing for introns in the genomic sequence and a relatively small number of sequencing errors. A freely available computer program, described herein, solves the problem for a 100-kb genomic sequence in a few seconds on a workstation.