Ultraselective transcatheter arterial chemoembolization with a 2-F tip microcatheter for small hepatocellular carcinomas: Relationship between local tumor recurrence and visualization of the portal vein with iodized oil
Ultraselective transcatheter arterial chemoembolization with a 2-F tip microcatheter for small hepatocellular carcinomas: Relationship between local tumor recurrence and visualization of the portal vein with iodized oil
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DOI：
10.1016/j.jvir.2006.12.004
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发表时间：
2007-03-01
影响因子：
2.9
通讯作者：
Mitsui, Takeshi
中科院分区：
文献类型：
--
作者：
Miyayama, Shiro;Matsui, Osamu;Mitsui, Takeshi
目的：探讨超选择性肝动脉化疗栓塞术治疗小肝癌与门静脉碘油沉积的关系。材料与方法：对123例直径小于5 cm的小肝癌(平均直径1.9 cm，中位直径1.6 cm)采用2-F针尖微导管在肝段动脉远端行肝动脉化疗栓塞术。TACE术中门静脉显影分为3级：0=未显示，1=局限于肿瘤附近，2=完整或延伸至栓塞区。比较各分级组的局部复发率。复发方式可分为瘤内复发和瘤周复发。结果：123个肿瘤中，2级53个(43.1%)，1级52个(42.3%)，0级18个(14.6%)。术后12、24和36个月的总局部复发率分别为25.6%、34.7%和34.7%。2、1、0级组12个月的局部复发率分别为7.9%、24.8%、85.7%，24个月时分别为17.7%、38.9%、85.7%。2级组复发率明显低于1级组和0级组(P=0.0485和P
PURPOSE: To retrospectively evaluate the relationship between local tumor recurrence and iodized oil deposition in the portal vein by using ultraselective transcatheter arterial chemoembolization (TACE) for small hepatocellular carcinoma.MATERIALS AND METHODS: One-hundred twenty-three tumors smaller than 5 cm in diameter (mean diameter, 1.9 cm; median diameter, 1.6 cm) were treated with TACE by using a 2-F tip microcatheter at a distal portion of the subsegmental artery of the liver. Portal vein visualization at spot radiography during TACE was divided into three grades, as follows: 0 = not visualized, 1 = limited near the tumor, and 2 = whole or extended to the embolized area. Local recurrence rates of each grade group were compared. The recurrent pattern was divided into intratumoral and peritumoral recurrence. Complications were also analyzed.RESULTS: Of the 123 tumors, 53 (43.1%) were classified as grade 2, 52 (42.3%) were classified as grade 1, and 18 (14.6%) tumors were classified as grade 0. Overall local recurrence rates at 12, 24, and 36 months were 25.6%, 34.7%, and 34.7%, respectively. The local recurrence rates for the grades 2, 1, and 0 groups were 7.9%, 24.8%, and 85.7%, respectively, at 12 months and 17.7%, 38.9%, and 85.7% at 24 months. Recurrence rates in the grade 2 group were significantly lower than those in the grades 1 and 0 groups (P =.0485 and P