DR2–NEGATIVE NARCOLEPSY
DR2–NEGATIVE NARCOLEPSY
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DR2——阴性发作性睡病
DOI：
10.1016/s0140-6736(86)90188-1
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发表时间：
1986
期刊：
影响因子：
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通讯作者：
P. Geisler
中科院分区：
文献类型：
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作者：
A. Andreas;S. Scholz;E. Keller;E. Albert;B. Roth;S. Nevsimalova;K. Šonka;P. Docekal;E. Ivašková;H. Schulz;P. Geisler
正在进一步评估此处使用的 DNA 杂交方法的灵敏度和特异性。然而，从这些初步观察结果来看，HPV DNA似乎存在于一些低风险区域的食管癌中，并且HPV作为食管癌可能的病因学因素值得进一步研究。从石蜡包埋材料中提取的 DNA 杂交可应用于不同身体部位的档案组织，为检测病毒 DNA 以及组织中的其他 DNA 提供简单的筛选测试。西澳大利亚大学微生物学系，伊丽莎白二世女王医疗中心，尼德兰，西澳大利亚 6009
The DNA hybridisation method used here is being further evaluated for sensitivity and specificity. However, from these preliminary observations it seems that HPV DNA is present in some oesophageal carcinomas in a low-risk area and that HPV is worthy of further investigation as a possible aetiological factor in oesophageal carcinoma. Hybridisation of DNA extracted from paraffin-embedded material could be applied to archival tissue from various body sites, offering a simple screening test for the detection of viral DNA and, perhaps, other DNA in tissues. Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6009