REDUCTION OF MAGNETIC RESONANCE IMAGING-RELATED HEATING IN DEEP BRAIN STIMULATION LEADS USING A LEAD MANAGEMENT DEVICE
REDUCTION OF MAGNETIC RESONANCE IMAGING-RELATED HEATING IN DEEP BRAIN STIMULATION LEADS USING A LEAD MANAGEMENT DEVICE
复制标题
DOI：
10.1227/01.neu.0000176877.26994.0c
复制
发表时间：
2005-10-01
期刊：
影响因子：
4.8
通讯作者：
Rezai, Ali R.
中科院分区：
文献类型：
--
作者：
Baker, Kenneth B.;Tkach, Jean;Rezai, Ali R.
目的：评估导线管理装置减少磁共振成像 (MRI) 相关的深部脑刺激 (DBS) 导线发热的能力，从而降低植入这些植入物的患者接受 MRI 操作的风险。 方法：使用 Activa 系列（Medtronic, Inc.，明尼苏达州明尼阿波利斯）DBS 系统在体外凝胶盐水头部和躯干中进行实验 幻影。在使用 1.5 T 的发射和接收射频身体线圈和 3 T 的发射和接收射频头部线圈进行 MRI 期间，使用荧光测温法记录温度变化。放置在体模中的颅骨模型用于测试定制设计的钻孔装置，该装置允许在 DBS 引线退出引线时在 DBS 引线处的钻孔周围放置小直径同心环。 结果：总共进行了 41 次扫描，绝对温度变化范围为 0.8 至 10.3°C。根据测试的 MRI 系统和放置硬件的体模侧面，循环放置导致温升降低了 41% 至 74%。在测试范围（0-2.75 个环）内，效果与形成的环数量呈线性相关（P < 0.01）。 结论：围绕钻孔放置的小同心环似乎减少了这些植入物与 MRI 相关的发热。尽管其机制尚未完全了解，但本研究中使用的设备除了可以提高患者的安全系数外，还可以允许在 1.5 T 和 3 T 的患者中使用更广泛的临床扫描序列。
OBJECTIVE: To evaluate the ability of a lead management device to reduce magnetic resonance imaging (MRI)-related heating of deep brain stimulation (DBS) leads and thereby to decrease the risks of exposing patients with these implants to MRI procedures.METHODS: Experiments were performed using the Activa series (Medtronic, Inc., Minneapolis, MN) DBS systems in an in vitro, gelled-saline head and torso phantom. Temperature change was recorded using fluoroptic thermometry during MRI performed using a transmit-and-receive radiofrequency body coil at 1.5 T and a transmit-and-receive radiofrequency head coil at 3 T. A cranial model placed in the phantom was used to test a custom-designed burr hole device that permitted the placement of small-diameter, concentric loops around the burr hole at the DBS lead as it exited the cranium.RESULTS: A total of 41 scans were performed, with absolute temperature changes ranging from 0.8 to 10.3 C. Depending on the MRI system tested and the side of the phantom on which the hardware was placed, loop placement resulted in reductions in temperature rise of 41 to 74%. The effect was linearly related to the number of loops formed (P < 0.01) over the range tested (0-2.75 loops).CONCLUSION: Small, concentric loops placed around the burr hole seem to reduce MRI-related heating for these implants. Although the mechanism is still not fully understood, a device such as that used in the present study could permit a wider range of clinical scanning sequences to be used at 1.5 and 3 T in patients with DBS implants, in addition to increasing the margin of safety for the patient.