Report of two rare complications of pandemic influenza A (H1N1)
Report of two rare complications of pandemic influenza A (H1N1)
复制标题
DOI：
10.3855/jidc.1723
复制
发表时间：
2012-02-01
影响因子：
1.9
通讯作者：
Delavarian, Leila
中科院分区：
文献类型：
--
作者：
Babamahmoodi, Farhang;Davoodi, Ali Reza;Delavarian, Leila
新型甲型H1N1流感在出现后的短时间内就造成了全球性的重大健康问题。这种感染通常是自限性的，但有时会导致严重和致命的并发症。在这项研究中，我们介绍了两种罕见的甲型流感并发症，他们被转诊到伊朗北部的拉齐大学附属医院。第一例患者为一名 30 岁男性，患有剧烈头痛、高烧，并伴有寒战、全身肌痛和关节痛。脑脊液分析与无菌性脑膜炎一致。第二例病例为一名25岁孕妇，出现高烧、寒战、严重疲劳和不适，入院几小时后出现呼吸急促、心动过速、呼吸窘迫、发绀和意识丧失。超声心动图报告心肌心包炎。患者被转移到重症监护室并开始机械通气。第二天，患者开始阴道流血，三天后发展为自然流产。使用咽拭子的实时逆转录酶 PCR 证实新型甲型流感 (H1N1) 的诊断。
Novel influenza A (H1N1) has created a major worldwide health problem within a short time after its emergence. This infection is often self-limited, but sometimes can cause severe and fatal complications. In this study, we present two rare complications of pandemic influenza A, who were referred to Razi University Affiliated Hospital in northern Iran. The first case was a 30-year-old man with severe headache and high fever accompanied with chills, generalized myalgia, and arthralgia. Cerebrospinal fluid analysis was consistent with aseptic meningitis. The second case, a 25-year-old pregnant woman with high fever, chills and severe fatigue and malaise, developed tachypnea, tachycardia, respiratory distress, cyanosis and loss of consciousness a few hours after admission. Echocardiography reported myopericarditis. The patient was transferred to the intensive care unit and mechanical ventilation was begun. The next day, the patient started vaginal bleeding which progressed to spontaneous abortion three days later. Diagnosis of novel influenza A (H1N1) was confirmed using real-time reverse-transcriptase PCR of a pharyngeal swab.