Hexagonal boron nitride nanosheets as a multifunctional background-free matrix to detect small molecules and complicated samples by MALDI mass spectrometry
Hexagonal boron nitride nanosheets as a multifunctional background-free matrix to detect small molecules and complicated samples by MALDI mass spectrometry
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六方氮化硼纳米片作为多功能无背景基质，通过 MALDI 质谱检测小分子和复杂样品
DOI：
10.1039/c7cc02957h
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发表时间：
2017
影响因子：
4.9
通讯作者：
Nie Zongxiu
中科院分区：
文献类型：
--
作者：
Wang Jianing;Sun Jie;Wang Jiyun;Liu Huihui;Xue Jinjuan;Nie Zongxiu
在这里，我们报告了使用六方氮化硼（h-BN）纳米片作为全激光脉冲能量范围内的第一个无背景基质的创新，用于小分子代谢物的分析和成像，并作为样品富集的吸附剂。由于其完全游离的背景和作为吸附剂和基质的高效率，h-BN在代谢组学、MALDI成像和环境分析方面具有广阔的应用前景。
Here we report the innovation of using hexagonal boron nitride (h-BN) nanosheets as the first background-free matrix among the full laser pulse energy range for the analysis and imaging of small molecule metabolites and as an adsorbent for the enrichment of samples. Due to its totally free background and high efficiency as an adsorbent and matrix, h-BN has promising prospects in metabolomics, MALDI imaging, and environmental analysis.