Plaque Formation in Chick Embryo Fibroblast Cells by Chlamydia Isolated From Avian and Mammalian Sources
Plaque Formation in Chick Embryo Fibroblast Cells by Chlamydia Isolated From Avian and Mammalian Sources
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从禽类和哺乳动物来源分离的衣原体在鸡胚成纤维细胞中形成斑块
DOI：
10.1128/jb.98.2.475-480.1969
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发表时间：
1969
影响因子：
3.2
通讯作者：
F. Piraino
中科院分区：
文献类型：
--
作者：
F. Piraino
对15株衣原体（2株沙眼衣原体和13株鹦鹉热衣原体）在鸡胚成纤维细胞上进行了空斑形成试验。C.沙眼衣原体12株不形成空斑;鹦鹉热菌能形成空斑，1株不能形成空斑。C.研究了鹦鹉热菌株，发现12个菌株可初步分为三种空斑类型：小（<0.50 mm）、中等（0.50 - 0.90 mm）和大（>0.90 mm）。小斑块主要与菌株M56、ET、CP 3、CT 4、EBA、CS 1和CT 2相关。中等大小的空斑主要与菌株NJ 1、VT 1和H81相关。大斑块主要与菌株WC和OG相关。噬斑大小似乎与衣原体对实验动物的毒力有关。
Fifteen strains of chlamydial agents, 2 Chlamydia trachomatis and 13 Chlamydia psittaci, were tested for plaque formation on chick embryo fibroblast cells. C. trachomatis strains did not form plaques; 12 strains of C. psittaci did form plaques and 1 strain did not. The distribution of plaque sizes with C. psittaci strains was studied and it was found that the 12 strains could be tentatively grouped into three plaquing types: small (<0.50 mm), intermediate (0.50 to 0.90 mm), and large (>0.90 mm). Small plaques were predominantly associated with strains M56, ET, CP3, CT4, EBA, CS1, and CT2. Intermediate size plaques were predominantly associated with strains NJ1, VT1, and H81. Large plaques were predominantly associated with strains WC and OG. Plaque size appears to be related to virulence of Chlamydia for laboratory animals.