Vegetable but not fruit consumption reduces the risk of type 2 diabetes in Chinese women
Vegetable but not fruit consumption reduces the risk of type 2 diabetes in Chinese women
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DOI：
10.1093/jn/138.3.574
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发表时间：
2008-03-01
影响因子：
4.2
通讯作者：
Zheng, Wei
中科院分区：
文献类型：
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作者：
Villegas, Raquel;Shu, Xiao Ou;Zheng, Wei
我们在一项基于人群的前瞻性研究中检查了水果和蔬菜摄入量与2型糖尿病（T2 D）发病率之间的关系，该研究包括64，191名女性，这些女性在研究招募时没有T2 D或其他慢性疾病史，并且具有有效的饮食信息。饮食摄入量通过使用经验证的FFQ进行面对面访谈进行评估。在297，755人-年的随访期间，记录了1608例新发T2 D病例。我们使用考克斯回归模型来评估水果和蔬菜摄入量（g/d）与2型糖尿病风险的相关性。蔬菜摄入量与T2 D呈负相关。多变量分析显示，蔬菜摄入量高的五分位数与蔬菜摄入量低的五分位数相比，T2 D的相对危险度为0.72（95%CI：0.61-0.85; P < 0.01）。个别蔬菜组都与T2 D的风险呈负相关且显着相关。水果摄入量与该人群的糖尿病发病率无关。我们的数据表明，蔬菜消费可以防止T2 D的发展。
We examined associations between fruit and vegetable intake and the incidence of type 2 diabetes (T2D) in a population-based prospective study of 64,191 women with no history of T2D or other chronic diseases at study recruitment and with valid dietary information. Dietary intake was assessed by in-person interviews using a validated FFQ. During 297,755 person-years of follow-up, 1608 new cases of T2D were documented. We used a Cox regression model to evaluate the association of fruit and vegetable intake (g/d) with the risk of T2D. Quintiles of vegetable intake and T2D were inversely associated. The relative risk for T2D for the upper quintile relative to the lower quintile of vegetable intake was 0.72 (95% CI: 0.61-0.85; P < 0.01) in multivariate analysis. Individual vegetable groups were all inversely and significantly associated with the risk of T2D. Fruit intake was not associated with the incidence of diabetes in this population. Our data suggest that vegetable consumption may protect against the development of T2D.