A population-based cross-sectional study of the association between periodontitis and arterial stiffness among the older Japanese population
A population-based cross-sectional study of the association between periodontitis and arterial stiffness among the older Japanese population
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DOI：
10.1111/jre.12835
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发表时间：
2020-12-28
影响因子：
3.5
通讯作者：
Ogawa, Hiroshi
中科院分区：
文献类型：
--
作者：
Iwasaki, Masanori;Kimura, Yumi;Ogawa, Hiroshi
目的探讨日本老年人牙周炎与动脉僵硬之间的关系。动脉僵硬增加心血管事件和死亡、发病率和痴呆的风险。方法对一项横断面研究的数据进行二次分析，评估牙周炎症表面积(PISA)，反映通过全口牙周检查估计的牙周组织炎症数量。根据疾病控制中心/美国牙周学学会提供的参数来定义重度牙周炎。心脏-踝关节血管指数(CAVI)被用来测量动脉的整体硬度，CAVI越高表明动脉硬度增加。结果185名日本成年人[男性占35%；年龄，平均(标准差)80.2(4.4)岁]参与分析。平均PISA和重度牙周炎的患病率分别为64.4 mm(2)和27.6%；54(29.2%)，56(30.3%)和75(40.5%)的参与者被分层到洞穴9，9
Objective To investigate the potential association between periodontitis and arterial stiffness among the older Japanese population.Background The prevalence of periodontitis is increasing in Japanese older adults. Arterial stiffness increases the risks of cardiovascular events and death, morbidity, and dementia.Methods This secondary analysis of data from a cross-sectional study evaluated the periodontal inflamed surface area (PISA), reflecting the amount of inflamed periodontal tissue that was estimated by a full-mouth periodontal examination. Severe periodontitis was defined per the parameters provided by the Centers for Disease Control/American Academy of Periodontology. The Cardio-Ankle Vascular Index (CAVI) was used for measuring the overall stiffness of the artery, and higher CAVI indicated increased arterial stiffness. An ordinal logistic regression model was used to evaluate the association between periodontitis and arterial stiffness.Results The analysis included 185 Japanese adults [35% men; age, mean (standard deviation) 80.2 (4.4) years]. The average PISA and the prevalence of severe periodontitis were 64.4 mm(2) and 27.6%, respectively; 54 (29.2%), 56 (30.3%), and 75 (40.5%) participants were stratified to the CAVI < 9, 9