Colorimetric Detection of Pb2+ Using Glutathione Functionalized Gold Nanoparticles
Colorimetric Detection of Pb2+ Using Glutathione Functionalized Gold Nanoparticles
复制标题
使用谷胱甘肽功能化金纳米颗粒比色检测 Pb2
DOI：
10.1021/am100107k
复制
发表时间：
2010-05-01
影响因子：
9.5
通讯作者：
Su, Zhongmin
中科院分区：
文献类型：
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作者：
Chai, Fang;Wang, Chungang;Su, Zhongmin
利用谷胱甘肽功能化纳米金(GSH-GNPs)建立了一种简便、经济、灵敏的Pb2+比色检测方法。详细考察了检测的灵敏度和选择性。在Pb2+存在下，GSH-GNPs可以立即聚集，尤其是在加入1M的氯化钠水溶液后。Pb2+可以通过GNPs的比色反应来检测，这种比色反应可以用紫外可见分光光度计甚至肉眼来监测，检测下限可以达到100 nm。与其他金属离子(Hg2+、Mg2+、Zn2+、Ni2+、Cu2+、Co2+、Ca2+、Mn2+、Fe2+、Cd2+、Ba2+和Cr3+)相比，Pb2+结合的GSH-GNPs显示出良好的选择性，导致了明显的颜色变化。这为Pb2+的现场实时检测提供了一种简单有效的比色传感器(不含酶或DNA)。最重要的是，该探针还应用于湖泊样品中Pb2+的测定，干扰小，灵敏度高。
A facile, cost-effective and sensitive colorimetric detection method for Pb2+ has been developed by using glutathione functionalized gold nanoparticles (GSH-GNPs). The sensitivity and selectivity of detection were investigated in detail. The GSH-GNPs could be induced to aggregate immediately in the presence of Pb2+, especially after the addition of 1 M NaCl aqueous solution. The Pb2+ could be detected by colorimetric response of GNPs that could be monitored by a UV vis spectrophotometer or even naked eyes, and the detection limit could reach 100 nM. The GSH-GNPs bound by Pb2+ showed excellent selectivity compared to other metal ions (Hg2+, Mg2+, Zn2+, Ni2+, Cu2+, Co2+, Ca2+, Mn2+, Fe2+, Cd2+, Ba2+, and Cr3+), which led to prominent color change. This provided a simple and effective colorimetric sensor (no enzyme or DNA) for on-site and real-time detection of Pb2+. Most importantly, this probe was also applied to determine the Pb2+ in the lake samples with low interference and high sensitivity.