Sex differences in the clinical presentation, resource use, and 3-month outcome of acute stroke in Europe - Data from a multicenter multinational hospital-based registry
Sex differences in the clinical presentation, resource use, and 3-month outcome of acute stroke in Europe - Data from a multicenter multinational hospital-based registry
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DOI：
10.1161/01.str.0000068410.07397.d7
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发表时间：
2003-05-01
期刊：
影响因子：
8.3
通讯作者：
Inzitari, D
中科院分区：
文献类型：
--
作者：
Di Carlo, A;Lamassa, M;Inzitari, D
背景和目的：关于卒中患者治疗中存在性别差异的信息很少。我们评估了性别差异是否可能影响临床表现，资源使用，以及在欧洲多中心研究中风的结果。方法-在欧洲协调行动涉及7个国家，4499例首次在一生中中风住院的患者进行了人口统计学，危险因素，临床表现，资源使用，和3个月生存，残疾结果：2239例患者为男性，2260例为女性.与男性患者相比，女性患者明显年龄更大（平均年龄74.5 ± 12.5岁对69.2 ± 12.1岁），卒中前更常住院，卒中前兰金评分更差（所有值均P < 0.001）。高血压史（P = 0.007）、房颤史（P < 0.001）、昏迷史（P < 0.001）、瘫痪史（P
Background and Purpose - The information on the existence of sex differences in management of stroke patients is scarce. We evaluated whether sex differences may influence clinical presentation, resource use, and outcome of stroke in a European multicenter study.Methods - In a European Concerted Action involving 7 countries, 4499 patients hospitalized for first-in-a-lifetime stroke were evaluated for demographics, risk factors, clinical presentation, resource use, and 3-month survival, disability (Barthel Index), and handicap (Rankin Scale).Results - Overall, 2239 patients were males and 2260 females. Compared with males, female patients were significantly older (mean age 74.5 +/- 12.5 versus 69.2 +/- 12.1 years), more frequently institutionalized before stroke, and with a worse prestroke Rankin score (all values P < 0.001). History of hypertension ( P = 0.007) and atrial fibrillation ( P < 0.001) were significantly more frequent in female stroke patients, as were coma (P < 0.001), paralysis (P