Paracorporeal ventricular assist device as a bridge to transplant candidacy in the era of implantable continuous-flow ventricular assist device

Paracorporeal ventricular assist device as a bridge to transplant candidacy in the era of implantable continuous-flow ventricular assist device
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体外心室辅助装置是植入式连续流心室辅助装置时代移植候选者的桥梁

DOI:
10.1007/s10047-013-0731-3
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发表时间:
2013
期刊:
影响因子:
1.3
通讯作者:
Suwa H
Suwa H
中科院分区:
工程技术4区
文献类型:
--
作者:
Iwashima Y;Yanase M;Horio T;Seguchi O;Murata Y;Fujita T;Toda K;Kawano Y;Nakatani T;Suwa H

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心室辅助装置(VAD)长期以来一直被用作移植治疗(BTT)的桥梁。Nipro-Toyobo旁心搏动流VAD(nt-VAD)是唯一可用的器械,直到2011年4月植入式连续流VAD(cf-VAD)上市。虽然cf-VAD是BTT的核心,但nt-VAD仍然是必要的选择。我们的目标是阐明nt-VAD在cf-VAD使用不断增加的时代的作用。我们回顾性分析了2011年5月至2013年3月在美国国家心脑血管中心接受VAD植入术的患者。比较nt-VAD和cf-VAD组的特征。29例患者(平均年龄37.7 ± 11.1岁,23例男性)接受了VAD植入术。15例患者最初接受了nt-VAD,但4例转为cf-VAD。在这15例患者中,3例因体积过小而无法植入cf-VAD,2例需要双侧心室支持。其余10例患者接受了nt-VAD(7例患者为INTERMACS 1级,3例患者为2级)。与cf-VAD组相比,nt-VAD组患者的术前机械循环支持明显更多,并且在VAD植入前处于更危急的状态。2年生存率无显著差异。尽管nt-VAD患者病情危重,但其总生存期在统计学上并不劣于cf-VAD患者。nt-VAD是一个很好的选择,作为一个BTC的病人紧急和危重的条件。
Ventricular assist devices (VADs) have long been used as bridge to transplant therapy (BTT). Nipro-Toyobo paracorporeal pulsatile-flow VAD (nt-VAD) was the only device available until April 2011, when implantable continuous-flow VADs (cf-VADs) became available. Although cf-VADs are central to BTT, nt-VAD remains a necessary option. We aimed to clarify the role of nt-VAD in an era of increasing cf-VAD use. We retrospectively reviewed patients who underwent VAD implantation at the National Cerebral and Cardiovascular Center from May 2011 to March 2013. Characteristics were compared between the nt-VAD and cf-VAD groups. Twenty-nine patients (mean age 37.7 ± 11.1 years, 23 males) underwent VAD implantation. Fifteen patients initially received nt-VADs, although 4 were converted to cf-VADs. Of these 15 patients, 3 were too small for cf-VADs and 2 needed bilateral ventricular support. The remaining 10 patients received nt-VADs (7 patients at INTERMACS level 1 and 3 at level 2). The nt-VAD group patients had significantly more preoperative mechanical circulatory support and were in a more critical condition before VAD implantation than the cf-VAD group. The 2-year survival rate was not significantly different. Despite the critical conditions of nt-VAD patients, their overall survival is not statistically inferior to that of cf-VAD patients. nt-VAD is a good option as a BTC for the patient with urgent and critical condition.
将社区医院短期心室支持的心源性休克患者与三级医院长期心室支持联系起来。
DOI: 10.1016/j.healun.2012.01.863
发表时间: 2012
期刊: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
影响因子: --
作者:
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期刊: The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi
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期刊: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
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DOI: 10.1016/j.healun.2010.12.001
发表时间: 2011-02-01
影响因子: 8.9
作者:
Kirklin, James K.;Naftel, David C.;Young, James B.
通讯作者: Young, James B.
DOI: 10.1016/j.jacc.2009.03.055
发表时间: 2009-07-21
影响因子: 24
作者:
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通讯作者: Frazier, O. Howard