DIETARY AND OTHER RISK-FACTORS FOR STROKE IN HAWAIIAN JAPANESE MEN
DIETARY AND OTHER RISK-FACTORS FOR STROKE IN HAWAIIAN JAPANESE MEN
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DOI：
10.1161/01.str.16.3.390
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发表时间：
1985-01-01
期刊：
影响因子：
8.3
通讯作者：
YANO, K
中科院分区：
文献类型：
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作者：
KAGAN, A;POPPER, JS;YANO, K
作为一项正在进行的纵向研究的一部分，7895名居住在瓦胡岛的日本裔男性，年龄在45-68岁之间，在入组检查时没有中风的证据，随后进行了复查和监测。在10年的随访中，154人发生血栓栓塞性中风，65人发生颅内出血，19人发生不明类型中风。79人死于中风。血栓栓塞性卒中的独立危险因素有血压升高、葡萄糖耐受不良、年龄、左心室肥厚或紧张的心电图证据、吸烟和蛋白尿。与颅内出血风险增加相关的因素是年龄、血压升高、吸烟、血清尿酸，以及相反的血清胆固醇水平。心电图显示左心室肥厚或劳损显著增加脑出血的风险，但与蛛网膜下腔出血无关。在单变量分析中，膳食脂肪摄入量与血栓栓塞和总卒中发生率呈负相关。蛋白质摄入量与卒中总发生率也呈反比关系。在多变量分析中，这些饮食关系在统计学上不显著。没有发现盐摄入量与中风发病率之间的关系。
As part of an ongoing longitudinal study, 7895 men of Japanese ancestry living on the island of Oahu, aged 45-68 and free of evidence of prior stroke at entry examination, were followed by reexaminations and surveillance. During 10 yr of follow-up, 154 men developed thromboembolic stroke, 65 developed intracranial hemorrhage, and 19 developed stroke of unknown type. There were 79 deaths attributed to stroke. The independent risk factors for thromboembolic stroke were elevated blood pressure, glucose intolerance, age, ECG evidence of left ventricular hypertrophy or strain, cigarette smoking and proteinuria. Attributes associated with increased risk of intracranial hemorrhage were age, elevated blood pressure, cigarette smoking, serum uric acid and, inversely, serum cholesterol level. ECG evidence of left ventricular hypertrophy or strain significantly increased the risk of cerebral hemorrhage, but was not associated with subarachnoid hemorrhage. In univariate analysis, there was inverse relation between dietary fat intake and thromboembolic and total stroke incidence. An inverse relation was also shown between protein intake and total stroke incidence. These dietary relations became statistically not significant in multivariate analysis. No relation was found between salt intake and the incidence of stroke.