Language Exposure for Preterm Infants is Reduced Relative to Fetuses.
Language Exposure for Preterm Infants is Reduced Relative to Fetuses.
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与胎儿相比，早产儿的语言接触减少。
DOI：
10.1016/j.jpeds.2022.12.042
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Rollo,Derrick
中科院分区：
文献类型：
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作者：
Monson,BrianB;Ambrose,SophieE;Gaede,Carey;Rollo,Derrick
Objective评估早产和新生儿重症监护病房住院期间的语言和听觉暴露的变化和缺陷，并与典型发育胎儿的子宫内的听力暴露进行比较。研究设计我们分析了27例典型发育胎儿和24例早产儿的队列研究中超过23 000小时的听觉暴露数据。 通过让孕妇佩戴24小时录音设备来捕获胎儿的子宫外暴露。对于早产儿，将记录设备放置在婴儿床中。采用多水平线性回归分析婴儿性别、母亲文化程度和母亲职业对婴儿性别、母亲文化程度和母亲职业的影响。一个线性混合效应模型被用来测试扬声器gender.ResultsFetuses的效果被暴露在一个估计的2.6 ± 1.8小时/天附近，主要是女性的语言，近5倍大于32 ± 12分钟/天估计早产儿（P< .001）。早产儿每天暴露于电子声音（5.1 ± 2.5 vs 1.3 ± 0.6小时;P<0.001）和噪音（4.4 ± 2.1 vs 2.9 ± 2.8小时;P<0.05）的时间更长，每天安静的时间为4.7 ± 3.9小时。胎儿的语言和子宫外音暴露显示出明显的昼夜周期性模式，夜间暴露量较低，但早产儿的暴露量在24小时周期内变化明显较小（P< .001）。母亲的职业需要频繁的沟通预测更大的语言exposure（P< .05）。ConclusionsOur findings provides the first comparison of preterm infant auditory exposure to typically developing fetals.一些早产儿可能会在早产期间遭受超过150小时的语言暴露的缺陷。鉴于产前/早产儿语言暴露对神经行为结果的已知影响，这种程度的缺陷是令人担忧的。
ObjectiveTo assess changes and deficits in language and auditory exposures consequent to preterm birth and neonatal intensive care unit stay compared with exposuresin uteroamong typically developing fetuses.Study designWe analyzed over 23 000 hours of auditory exposure data in a cohort study of 27 typically-developing fetuses and 24 preterm infants. Extrauterine exposures for fetuses were captured by having pregnant women wear 24-hour audio recording devices. For preterm infants, recording devices were placed in the infant's crib. Multilevel linear regressions were conducted to test for group differences and effects of infant sex, maternal education, and mother' occupation. A linear mixed-effects model was used to test for an effect of speaker gender.ResultsFetuses were exposed to an estimated 2.6 ± 1.8 hours/day of nearby, predominantly female language, nearly 5 times greater than 32 ± 12 minutes/day estimated for preterm infants (P< .001). Preterm infants had greater daily exposure to electronic sounds (5.1 ± 2.5 vs 1.3 ± 0.6 hours;P< .001) and noise (4.4 ± 2.1 vs 2.9 ± 2.8 hours;P< .05), with 4.7 ± 3.9 hours/day of silence. Language and extrauterine sound exposure for fetuses showed a marked day/night cyclical pattern, with low exposure during nighttime hours, but preterm infants’ exposures showed significantly less change across the 24-hour cycle (P< .001). Maternal occupation requiring frequent communication predicted greater language exposure (P< .05).ConclusionsOur findings provide the first comparison of preterm infant auditory exposures to typically-developing fetuses. Some preterm infants may incur deficits of over 150 hours of language exposure over the preterm period. Given known effects of prenatal/preterm language exposure on neurobehavioral outcomes, this magnitude of deficit is alarming.