The Application of a New Model-Based Iterative Reconstruction in Low-Dose Upper Abdominal CT
The Application of a New Model-Based Iterative Reconstruction in Low-Dose Upper Abdominal CT
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DOI：
10.1016/j.acra.2018.11.020
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发表时间：
2019-10-01
影响因子：
4.8
通讯作者：
Zhang, Xirong
中科院分区：
文献类型：
--
作者：
Jia, Yongjun;Zhai, Bingying;Zhang, Xirong
基本原理和目标：比较上腹部计算机断层扫描（CT）的图像质量的新模型为基础的迭代重建（MBIR）与低对比度分辨率偏好（MBIRNR 40），传统的MBIR（MBIRc），自适应统计迭代重建（ASIR）在低剂量与ASIR在routine-dose.Materials和方法：研究包括体模和60例患者进行初始和后续CT扫描。对于患者，初始扫描以常规剂量（噪声指数= 10 HU）采集延迟相，随访时以低剂量（噪声指数= 20 HU）采集延迟相。低剂量CT采用40%和60%ASIR、MBIRc和MBIRNR 40重建，常规剂量CT采用40%ASIR重建。采用单因素方差分析比较皮下脂肪、背部肌肉、肝脏和脾脏实质的CT值和噪声测量值。两名放射科医师使用半定量7级（3至+3）率图像质量和artifaction.Results：幻影研究显示上级低对比度分辨率MBIRNR 40。对于患者扫描，低剂量CT的CT剂量指数为3.00 +/- 1.32 mGy，比常规剂量CT的11.90 +/- 4.75 mGy低75%。低剂量MBIRNR 40图像的图像噪声显著低于低剂量MBIRc和ASIR图像以及常规剂量ASIR图像（p < 0.05）。主观评级显示低剂量MBIRNR 40的图像质量更高，噪声更低，腹部结构的低对比度分辨率更好，病变轮廓比低剂量MBIRc和ASIR图像以及常规剂量ASIR图像更精细结论：MBIRNR 40在低剂量腹部CT中具有低对比度分辨率偏好，其图像质量明显优于MBIRc和ASIR;客观和主观图像质量显著优于常规剂量ASIR（剂量减少75%）。
Rationale and Objectives: To compare upper abdominal computed tomography (CT) image quality of new model-based iterative reconstruction (MBIR) with low-contrast resolution preference (MBIRNR40), conventional MBIR (MBIRc), and adaptive statistical iterative reconstruction (ASIR) at low dose with ASIR at routine-dose.Materials and Methods: Study included phantom and 60 patients who had initial and follow-up CT scans. For patients, the delay phase was acquired at routine-dose (noise index = 10 HU) for the initial scan and low dose (noise index = 20 HU) for the follow-up. The low-dose CT was reconstructed with 40% and 60% ASIR, MBIRc, and MBIRNR40, while routine-dose CT was reconstructed with 40% ASIR. CT value and noise measurements of the subcutaneous fat, back muscle, liver, and spleen parenchyma were compared using one-way ANOVA. Two radiologists used semiquantitative 7-scale (3 to +3) to rate image quality and artifacts.Results: The phantom study revealed superior low-contrast resolution with MBIRNR40. For patient scans, the CT dose index for the lowdose CT was 3.00 +/- 1.32 mGy, 75% lower than the 11.90 +/- 4.75 mGy for the routine-dose CT. Image noise for the low-dose MBIRNR40 images was significantly lower than the low-dose MBIRc and ASIR images, and routine-dose ASIR images (p < 0.05). Subjective ratings showed higher image quality for low-dose MBIRNR40, with lower noise, better low-contrast resolution for abdominal structures, and finer lesion contours than those of low-dose MBIRc and ASIR images, and routine-dose ASIR images (p < 0.05).Conclusion: MBIRNR40 with low-contrast resolution preference provides significantly lower noise and better image quality than MBIRc and ASIR in low-dose abdominal CT; significantly better objective and subjective image quality than the routine-dose ASIR with 75% dose reduction.