USUAL INTERSTITIAL PNEUMONIA - CORRELATION OF CT WITH CLINICAL, FUNCTIONAL, AND RADIOLOGIC FINDINGS
USUAL INTERSTITIAL PNEUMONIA - CORRELATION OF CT WITH CLINICAL, FUNCTIONAL, AND RADIOLOGIC FINDINGS
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DOI：
10.1148/radiology.162.2.3797650
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发表时间：
1987-02-01
期刊：
影响因子：
19.7
通讯作者：
MILLER, RR
中科院分区：
文献类型：
--
作者：
STAPLES, CA;MULLER, NL;MILLER, RR
通过回顾 23 名普通间质性肺炎 (UIP) 患者的临床数据、肺功能测试、胸片和 CT 扫描，获得了计算机断层扫描 (CT) 扫描的疾病程度与临床和功能损伤严重程度之间的相关性。 CT 扫描和胸部 X 光片均由两名独立观察者读取两次。通过 CT 扫描的视觉评分（0%-100% 累及肺实质）和 X 光片上的国际劳工局分类来评估疾病程度。 CT 和 X 光片评分在观察者内和观察者间均具有良好的一致性（所有 r .gtoreq. .71）。 CT 扫描可以更好地估计疾病范围，并且比 X 光片显示出更广泛的蜂窝状结构。通过 CT 评估的疾病范围与呼吸困难的严重程度之间存在显着相关性 (r = .62，P < .001)，并且 CT 与通过弥散能力评估的气体交换受损之间也存在显着相关性 (r = .64，P < .001)。通过胸部X光检查评估的疾病严重程度与临床和功能变量之间的相关性较差（所有r≤0.39）。
Correlation between disease extent on computed tomographic (CT) scans and severity of clinical and functional impairment was obtained in 23 patients with usual interstitial pneumonia (UIP) by review of the clinical data, pulmonary function tests, chest radiographs, and CT scans. The CT scans and chest radiographs were each read twice by two independent observers. Disease extent was assessed on CT scans by a visual score (0%-100% involvement of the lung parenchyma) and on the radiograph by the International Labour Office classification. There was good intraobserver and interobserver agreement for both CT and radiograph scores (all r .gtoreq. .71). CT scans gave a better estimate of disease extent and showed more extensive honeycombing than did the radiograph. A significant correlation was found between the extent of disease as assessed with CT and the severity of dyspnea (r = .62, P < .001), as well as between CT and impairment in gas exchange as assessed by the diffusing capacity (r = .64, P < .001). There was poor correlation between disease severity as assessed with chest radiography and the clinical and functional variables (all r .ltoreq. .39).