DASH lowers blood pressure in obese hypertensives beyond potassium, magnesium and fibre

DASH lowers blood pressure in obese hypertensives beyond potassium, magnesium and fibre
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DOI:
10.1038/jhh.2009.58
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发表时间:
2010-04-01
影响因子:
2.7
通讯作者:
Egan, B. M.
Egan, B. M.
中科院分区:
医学4区
文献类型:
--
作者:
Al-Solaiman, Y.;Jesri, A.;Egan, B. M.

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抗高血压饮食疗法(DASH)研究中的高水果和蔬菜部分降低血压的机制尚不清楚,但可能包括钾、镁和纤维。这项研究旨在将患有代谢综合征的腹型肥胖者(肥胖高血压患者)的血压从DASH的其他成分中分离出来。共有15名肥胖高血压患者和15名瘦血压正常者在标准的普通饮食中进行了研究,随机分为DASH或普通饮食,添加钾、镁和纤维以匹配DASH,然后交换到补充饮食。所有的饮食都是3周长的,等热量,钠和钙匹配。肥胖高血压患者服用DASH 3周后,血压低于正常饮食(-7.6±-1.4/-5.3+/-1.4 mm Hg,P
The mechanism underlying blood pressure (BP) reduction in the high fruits and vegetables arm of the Dietary Approaches to Stop Hypertension (DASH) study is unknown but may include potassium, magnesium and fibre. This study was designed to separate minerals and fibre from other components of DASH on BP in abdominally obese individuals with metabolic syndrome with pre-hypertension to stage 1 hypertension (obese hypertensives). A total of 15 obese hypertensives and 15 lean normotensives were studied on a standardized usual diet, randomized to DASH or usual diet supplemented with potassium, magnesium and fibre to match DASH, then crossed over to the complementary diet. All diets were 3 weeks long, isocaloric and matched for sodium and calcium. In obese hypertensives, BP was lower after 3 weeks on DASH than usual diet (-7.6 +/- 1.4/-5.3 +/- 1.4mmHg, P