Filamentous phage structure, infection and assembly
Filamentous phage structure, infection and assembly
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DOI：
10.1016/s0959-440x(98)80032-8
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发表时间：
1998-04-01
影响因子：
6.8
通讯作者：
Marvin, DA
中科院分区：
文献类型：
--
作者：
Marvin, DA
通过 X 射线纤维衍射得出的丝状噬菌体的结构模型得到了光谱和遗传实验的支持。噬菌体末端受体结合域的结构和噬菌体编码的细胞内 DNA 结合蛋白的结构已以高分辨率确定。最近通过遗传和生化分析对病毒生命周期的剖析，结合结构信息，提出了病毒感染和组装的模型。
The structural model of filamentous phage derived by X-ray fibre diffraction is supported by spectroscopic and genetic experiments. The structure of the receptor-binding domain at the end of the phage and the structure of the phage-coded intracellular DNA-binding protein have been determined at high resolution. The recent dissection of the virus life cycle by genetic and biochemical analyses, combined with structural information, suggests models for virus infection and assembly.