Risk assessment:: A model for predicting cross-species transmission of simian foamy virus from macaques (M-fascicularis) to humans at a monkey temple in Bali, Indonesia
Risk assessment:: A model for predicting cross-species transmission of simian foamy virus from macaques (M-fascicularis) to humans at a monkey temple in Bali, Indonesia
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DOI：
10.1002/ajp.20299
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发表时间：
2006-09-01
影响因子：
2.4
通讯作者：
Schillaci, Michael
中科院分区：
文献类型：
--
作者：
Engel, Gregory;Hungerford, Laura L.;Schillaci, Michael
在亚洲，人类和非人灵长类动物（NHP）之间的接触经常发生在猴庙（与自由放养的NHP群体有关的宗教场所），这可能会造成NHP-人类疾病传播。2003年3月，一个多学科专家小组参加了一个讲习班，该讲习班的目的是建立国家卫生计划-人类病原体传播风险模型。该小组开发了一个风险评估模型，以描述猴泡沫病毒（SFV）从寺庙猕猴（Macaca fascicularis）到猴庙游客的跨物种传播的可能性。SFV是一种地方性猿猴逆转录病毒，已被证明可从NHP传播给人类。在操作模型现场数据，实验室数据和专家意见被用来估计在这种情况下SFV传播的可能性。该模型为讨论作为风险评估工具的建模以及准确预测传播所需的数据类型奠定了基础。(c)2006 Wiley-Liss，Inc.
Contact between humans and nonhuman primates (NHPs) frequently occurs at monkey temples (religious sites that have become associated with free-ranging populations of NHPs) in Asia, creating the potential for NHP-human disease transmission. In March 2003 a multidisciplinary panel of experts participated in a workshop designed to model the risk of NHP-human pathogen transmission. The panel developed a risk assessment model to describe the likelihood of cross-species transmission of simian foamy virus (SFV) from temple macaques (Macaca fascicularis) to visitors at monkey temples. SFV is an enzootic simian retrovirus that has been shown to be transmitted from NHPs to humans. In operationalizing the model field data, laboratory data and expert opinions were used to estimate the likelihood of SFV transmission within this context. This model sets the stage for a discussion about modeling as a risk assessment tool and the kinds of data that are required to accurately predict transmission. (c) 2006 Wiley-Liss, Inc.