Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction

Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction
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DOI:
10.1038/sj.ijir.3900472
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发表时间:
1999-12-01
影响因子:
2.6
通讯作者:
Pe単a, BM
Pe単a, BM
中科院分区:
医学3区
文献类型:
--
作者:
Rosen, RC;Cappelleri, JC;Pe単a, BM

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国际勃起功能指数(IIEF)的15个项目的简化版本(IIEF-5)的开发,以诊断勃起功能障碍(艾德)的存在和严重程度。选择的五个项目是基于识别艾德的存在或不存在的能力,并坚持国家卫生研究所的ED定义。这些项目集中在勃起功能和性交满意度。对1152例男性(1036例艾德,116例对照)进行分析,受试者工作特征曲线表明IIEF-5是一种极好的诊断试验。基于艾德和无艾德的错误分类率相等,21分的临界值(分数范围,5-25)区分最好(灵敏度= 0.98,特异性= 0.88)。艾德分为五个严重程度等级,从无(22-25)到重度(5-7)。预测值和“真实”艾德分类之间存在实质性一致性(加权kappa = 0.82)。这些数据表明,IIEF-5具有良好的性能,用于检测ED的存在和严重程度。
An abridged five-item version of the 15-item International Index of Erectile Function (IIEF) was developed (IIEF-5) to diagnose the presence and severity of erectile dysfunction (ED). The five items selected were based on ability to identify the presence or absence of ED and on adherence to the National Institute of Health's definition of ED. These items focused on erectile function and intercourse satisfaction. For 1152 men (1036 with ED, 116 controls) analyzed, a receiver operating characteristic curve indicated that the IIEF-5 is an excellent diagnostic test. Based on equal misclassification rates of ED and no ED, a cutoff score of 21 (range of scores, 5-25) discriminated best (sensitivity = 0.98, specificity = 0.88). ED was classified into five severity levels, ranging from none (22-25) through severe (5-7). Substantial agreement existed between the predicted and 'true' ED classes (weighted kappa = 0.82). These data suggest that the IIEF-5 possesses favorable properties for detecting the presence and severity of ED.