Regioselective synthesis of fused oxazepinone scaffolds through one-pot Smiles rearrangement tandem reaction.
Regioselective synthesis of fused oxazepinone scaffolds through one-pot Smiles rearrangement tandem reaction.
复制标题
DOI：
10.1021/co2001058
复制
发表时间：
2011-08
影响因子：
--
通讯作者：
Yanli Liu;Chun-Yan Chu;Aiping Huang;Chunjing Zhan;Ying Ma;Chen Ma
中科院分区：
文献类型：
--
作者：
Yanli Liu;Chun-Yan Chu;Aiping Huang;Chunjing Zhan;Ying Ma;Chen Ma
本文介绍了一种方便、简便的区域选择性合成融合恶西平酮支架的方法。该工艺是一种通过一锅偶联/Smiles重排/环化方法高效构建恶西平酮支架的方法。这种过渡无金属工艺在合成生物和医学相关化合物方面具有潜在的应用前景。
The paper describes a convenient and facile methodology for the regioselective synthesis of fused oxazepinone scaffolds. This process is an efficient construction of the oxazepinone scaffold by a one-pot coupling/Smiles rearrangement/cyclization approach. This transition metal-free process has potential applications in the synthesis of biologically and medicinally relevant compounds.