Effects of Low-Level Laser Therapy on Pain and Scar Formation After Inguinal Herniation Surgery: A Randomized Controlled Single-Blind Study
Effects of Low-Level Laser Therapy on Pain and Scar Formation After Inguinal Herniation Surgery: A Randomized Controlled Single-Blind Study
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DOI：
10.1089/pho.2009.2548
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发表时间：
2010-06-01
影响因子：
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通讯作者：
Casarotto, Raquel Aparecida
中科院分区：
文献类型：
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作者：
de Paiva Carvalho, Rodrigo Leal;Alcantara, Paulo Sergio;Casarotto, Raquel Aparecida
目的：本研究的目的是探讨波长为 830 nm 的红外 GaAlAs 激光在腹股沟疝术后疤痕形成过程中的疗效。背景：正如之前在组织培养和动物实验中所证明的那样，低强度激光疗法（LLLT）已被证明对组织修复过程有益。然而，目前还缺乏关于使用红外 830 nm GaAlAs 激光进行 LLLT 对人体切口术后疤痕影响的研究。方法：28例接受腹股沟疝手术的患者随机分为实验组（G1）和对照组（G2）。 G1 接受 LLLT，第一次应用在手术后 24 小时进行，然后在第 3、5 和 7 天进行。使用 830 nm 二极管激光器照射切口，连续输出功率为 40 mW，光斑孔径为 0.08 cm(2)，持续 26 s，每点能量为 1.04 J，能量密度为 13 J/cm(2)。每个疤痕照射十个点。手术后六个月，两组均使用温哥华疤痕量表（VSS）、视觉模拟量表和疤痕厚度测量进行重新评估。结果：与 G2（4.85 +/- 1.87）相比，G1 在 VSS 总分中显示出明显更好的结果（2.14 +/- 1.51）；厚度测量值 (0.11 cm) 与 G2 (0.19 cm) 相比；与G2（1.07）相比，延展性（0.14）。 G2 的疼痛评分也高出 50% 左右。结论：腹股沟疝术后应用红外线LLLT（830 nm）可有效预防瘢痕疙瘩的形成。此外，LLLT 还能改善术后 6 个月的疤痕外观和质量。
Objective: The aim of this study was to investigate the efficacy of an infrared GaAlAs laser operating with a wavelength of 830 nm in the postsurgical scarring process after inguinal-hernia surgery. Background: Low-level laser therapy (LLLT) has been shown to be beneficial in the tissue-repair process, as previously demonstrated in tissue culture and animal experiments. However, there is lack of studies on the effects of LLLT on postsurgical scarring of incisions in humans using an infrared 830-nm GaAlAs laser. Method: Twenty-eight patients who underwent surgery for inguinal hernias were randomly divided into an experimental group (G1) and a control group (G2). G1 received LLLT, with the first application performed 24 h after surgery and then on days 3, 5, and 7. The incisions were irradiated with an 830-nm diode laser operating with a continuous power output of 40 mW, a spot-size aperture of 0.08 cm(2) for 26 s, energy per point of 1.04 J, and an energy density of 13 J/cm(2). Ten points per scar were irradiated. Six months after surgery, both groups were reevaluated using the Vancouver Scar Scale (VSS), the Visual Analog Scale, and measurement of the scar thickness. Results: G1 showed significantly better results in the VSS totals (2.14 +/- 1.51) compared with G2 (4.85 +/- 1.87); in the thickness measurements (0.11 cm) compared with G2 (0.19 cm); and in the malleability (0.14) compared with G2 (1.07). The pain score was also around 50% higher in G2. Conclusion: Infra-red LLLT (830 nm) applied after inguinal-hernia surgery was effective in preventing the formation of keloids. In addition, LLLT resulted in better scar appearance and quality 6 mo postsurgery.