Petrous carotid canal stenosis in malignant osteopetrosis: CT documentation with MR angiographic correlation
Petrous carotid canal stenosis in malignant osteopetrosis: CT documentation with MR angiographic correlation
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DOI：
10.1148/radiology.199.2.8668787
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发表时间：
1996-05-01
期刊：
影响因子：
19.7
通讯作者：
Gross, AJ
中科院分区：
文献类型：
--
作者：
Cure, JK;Key, LL;Gross, AJ
目得：研究岩颈动脉管（PCC）和颈内动脉（伊卡）狭窄的恶性osteopetrosi.MATERIALS和METHODS患者之间的关联：平均和最小PCC直径从颅计算机断层扫描（CT）扫描20例患者进行了比较，在52个对照组类似的测量。伊卡口径，磁共振（MR）动脉造影评价，与年龄和PCC dimensions.Results：有一个患者和对照PCC直径之间的统计学显着差异。在对照组中，年龄与PCC直径呈强正相关，而在患者中仅呈弱正相关。在所有患者的MR动脉造影上，一个或两个ICA狭窄。结论PCC和伊卡狭窄多见于恶性石骨症患者。骨过度生长或“持续胎儿状态”可能导致PCC狭窄。研究结果不支持这些患者进行性FCC狭窄。
PURPOSE: To study the association between petrous carotid canal (PCC) and internal carotid artery (ICA) stenoses in patients with malignant osteopetrosis.MATERIALS AND METHODS: Mean and minimum PCC diameters obtained from cranial computed tomographic (CT) scans in 20 patients were compared with similar measurements in 52 control subjects. ICA caliber, evaluated with magnetic resonance (MR) arteriography, was correlated with age and PCC dimensions.RESULTS: There was a statistically significant difference between patient and control PCC diameters. There was a strong positive correlation between age and PCC diameter in the control subjects, but only a weakly positive correlation in the patients. One or both ICAs were stenotic on all patient MR arteriograms. MR angiographic stenosis grade correlated positively with age but not with PCC diameters.CONCLUSION PCC and ICA stenoses occur frequently in patients with malignant osteopetrosis. Bony overgrowth or a ''persistent fetal state'' may produce the PCC stenoses. The findings do not support progressive FCC narrowing in these patients.