A numeric index based on spatial frequency for the tortuosity of retinal vessels and its application to plus disease in retinopathy of prematurity
A numeric index based on spatial frequency for the tortuosity of retinal vessels and its application to plus disease in retinopathy of prematurity
复制标题
DOI：
10.1097/00006982-199515060-00006
复制
发表时间：
1995-01-01
影响因子：
3.3
通讯作者：
Freedman, SF
中科院分区：
文献类型：
--
作者：
Capowski, JJ;Kylstra, JA;Freedman, SF
背景：在早产儿视网膜病变（ROP）中，眼底后极附近的血管迂曲是一个重要的临床体征，但临床医生很难估计血管的迂曲程度。 方法：作者设计了一种客观的、数字化的视网膜血管迂曲指数，该指数对 ROP 中发生的血管结构变化特别敏感，但对非 ROP 变化不是特别敏感。使用计算机软件根据眼底图像计算指数；这些图像的质量是作者在早产儿托儿所记录的照片或录像带帧的典型质量。结果：该指数可靠地将弯曲的血管与非弯曲的血管分开，并将达到 ROP 治疗阈值的眼睛与未达到 ROP 治疗阈值的眼睛分开。结论：该指数形成了 ROP 疾病状态的客观衡量标准。其计算仅需要血管片段，因此可能适用于从眼底图像中自动提取血管部分的成像系统。
Background: In retinopathy of prematurity (ROP), tortuosity of vessels near the posterior pole of the fundus is an important clinical sign, yet clinicians have difficulty estimating how tortuous the vessels are.Methods: The authors have devised an objective, numeric index of retinal blood vessel tortuosity that is especially sensitive to the structural changes in vessels that occur in ROP, but it is not particularly sensitive to non-ROP changes. Computer software is used to calculate the index from fundus images; the quality of these images is typical of photographs or videocassette frames that the authors record in the premature nursery.Results: The index reliably segregates tortuous vessels from nontortuous ones and separates eyes that reach ROP treatment threshold from eyes that do not.Conclusions: The index forms an objective measure of the ROP disease state. Its calculation requires only segments of vessels and thus, is potentially adaptable to imaging systems that automatically extract vessel portions from fundus images.