[Effects of Spasfon on course of labor].
[Effects of Spasfon on course of labor].
复制标题
DOI：
--
复制
发表时间：
2004-09
期刊：
影响因子：
--
通讯作者：
Yan Hao;G. Zhai;A. Duan
中科院分区：
文献类型：
--
作者：
Yan Hao;G. Zhai;A. Duan
目的观察斯帕丰对改善宫颈扩张、促进产程进展的作用。方法将97例宫颈水肿的正常产妇随机分为斯帕丰组（A组，n = 46）和阿托品组（B组，n = 51）。A组静注Spasfon 80 mg，B组宫颈内注射阿托品0.5 mg。结果（1）用药至宫颈完全扩张的平均时间为A组为（3.1 +/- 0.3）h，B组（4.4 +/- 0.4）h（P 0.05）; A组2小时之间的宫颈平均扩张为（4.3 +/- 0.2）cm，而B组为（2.5 +/- 0.3）cm（P 0.05）。(5)两组羊水颜色、新生儿窒息情况、新生儿体重差异无统计学意义（P > 0.05）。(6)两组产后出血发生率差异无统计学意义（P > 0.05）。结论斯帕丰能有效改善产程中宫颈扩张，母婴耐受性良好。
OBJECTIVE To observe the effects of Spasfon on improving dilatation of cervix and promoting the progression of labor. METHODS Ninety seven normal primiparae with cervical edema were randomly divided into Spasfon group (group A, n = 46) and atropine group (group B, n = 51) when the cervix dilated 2 - 3 cm. Group A was given 80 mg of Spasfon intravenously, and group B was injected atropine 0.5 mg into the cervix. RESULTS (1) The mean time period from drug administration to full dilation of the cervix was (3.1 +/- 0.3) h in group A, and (4.4 +/- 0.4) h in group B (P 0.05); the mean dilatation of cervix between the 2 hours in group A was (4.3 +/- 0.2) cm, while in group B it was (2.5 +/- 0.3) cm (P 0.05). (5) There was no statistically significant difference in the color of amniotic fluid, suffocation state and weight of the newborns between the two groups (P > 0.05). (6) There was no statistically significant difference in postpartum hemorrhage between the two groups, either (P > 0.05). CONCLUSION Spasfon can effectively improve cervical dilatation during labor and it is well tolerated by both mother and newborn.