Physical function as a prognostic biomarker among cancer survivors
Physical function as a prognostic biomarker among cancer survivors
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DOI：
10.1038/bjc.2014.568
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发表时间：
2015-01-06
影响因子：
8.8
通讯作者：
Harhay, M. N.
中科院分区：
文献类型：
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作者：
Brown, J. C.;Harhay, M. O.;Harhay, M. N.
背景资料：我们测试的假设，客观测量的身体功能预测癌症survivor.Methods之间的死亡率：我们评估了客观测量的身体功能，包括短的身体功能电池（SPPB）和快速步行速度在老年人cancer survivor.Results：在413癌症幸存者，315（76%）死亡的中位数随访11.0年。在多变量校正分析中，SPPB评分每增加1个单位，快速步行速度每增加0.1ms（-1），死亡率降低12%（风险比（HR）：0.88（95%置信区间（CI）：0.82-0.94）; P
Background: We tested the hypothesis that objectively measured physical function predicts mortality among cancer survivors.Methods: We assessed objectively measured physical function including the short physical performance battery (SPPB) and fast walk speed in older adult cancer survivors.Results: Among 413 cancer survivors, 315 (76%) died during a median follow-up of 11.0 years. In multivariable-adjusted analyses, each 1-unit increase in the SPPB score and 0.1ms(-1) increase in fast walk speed predicted a 12% reduction in mortality (hazard ratio (HR): 0.88 (95% confidence interval (CI): 0.82-0.94); P